[HTML][HTML] The genetic basis of autoimmunity seen through the lens of T cell functional traits
KA Lagattuta, HL Park, L Rumker, K Ishigaki… - Nature …, 2024 - nature.com
Autoimmune disease heritability is enriched in T cell-specific regulatory regions of the
genome. Modern-day T cell datasets now enable association studies between single …
genome. Modern-day T cell datasets now enable association studies between single …
[HTML][HTML] Inferring causal cell types of human diseases and risk variants from candidate regulatory elements
The heritability of human diseases is extremely enriched in candidate regulatory elements
(cRE) from disease-relevant cell types. Critical next steps are to infer which and how many …
(cRE) from disease-relevant cell types. Critical next steps are to infer which and how many …