Carboxylesterase-mediated imaging tool for diagnosis of liver injury and surgical resection navigation of pancreatic cancer

G Ma, Z Guo, X Zhang, H Zhang, Y Wang, J Li… - Sensors and Actuators B …, 2024 - Elsevier
The liver and pancreas are both very important digestive and metabolic organs. Once a
patient's liver and pancreas show lesions, such as accompanied by tumor proliferation or …

[HTML][HTML] Chronic treatment with glucagon-like peptide-1 and glucagon receptor co-agonist causes weight loss-independent improvements in hepatic steatosis in mice …

ER McGlone, DCD Hope, I Davies, M Dore… - Biomedicine & …, 2024 - Elsevier
Objectives Co-agonists at the glucagon-like peptide-1 and glucagon receptors
(GLP1R/GCGR) show promise as treatments for metabolic dysfunction-associated steatotic …

Identification of the first selective bioluminescent probe for real-time monitoring of carboxylesterase 2 in vitro and in vivo

Y Chen, T Zhao, Z Miao, T Huang, M Chen, Y Zhao… - Analyst, 2024 - pubs.rsc.org
Carboxylesterase (CES), a main hydrolysis enzyme family in the human body, plays a
crucial role in drug metabolism. Among them, CES1 and CES2 are the primary subtypes …