Combinatorial therapy in tumor microenvironment: where do we stand?
The tumor microenvironment plays a pivotal role in tumor initiation and progression by
creating a dynamic interaction with cancer cells. The tumor microenvironment consists of …
creating a dynamic interaction with cancer cells. The tumor microenvironment consists of …
[HTML][HTML] Immune evasion by cancer stem cells
H Tsuchiya, G Shiota - Regenerative Therapy, 2021 - Elsevier
Tumor immunity represents a new avenue for cancer therapy. Immune checkpoint inhibitors
have successfully improved outcomes in several tumor types. In addition, currently, immune …
have successfully improved outcomes in several tumor types. In addition, currently, immune …
A possible pathogenic role of Syndecan-1 in the pathogenesis of coronavirus disease 2019 (COVID-19)
S Karampoor, H Zahednasab, M Farahmand… - International …, 2021 - Elsevier
A cell-surface heparan proteoglycan called Syndecan-1 (SDC-1) has multiple roles in
healthy and pathogenic conditions, including respiratory viral infection. In this study, we …
healthy and pathogenic conditions, including respiratory viral infection. In this study, we …
HS, an ancient molecular recognition and information storage glycosaminoglycan, equips hs-proteoglycans with diverse matrix and cell-interactive properties …
Heparan sulfate is a ubiquitous, variably sulfated interactive glycosaminoglycan that
consists of repeating disaccharides of glucuronic acid and glucosamine that are subject to a …
consists of repeating disaccharides of glucuronic acid and glucosamine that are subject to a …
Research on liquid biopsy for cancer: A bibliometric analysis
S Jiang, Y Liu, Y Xu, X Sang, X Lu - Heliyon, 2023 - cell.com
Background: In recent years, liquid biopsy has shown great potential for improving cancer
diagnosis and treatment. This study aimed to explore the trends and prospects in liquid …
diagnosis and treatment. This study aimed to explore the trends and prospects in liquid …
Establishment and validation of a plasma oncofetal chondroitin sulfated proteoglycan for pan-cancer detection
PF Zhang, ZY Wu, WB Zhang, YQ He, K Chen… - Nature …, 2023 - nature.com
Various biomarkers targeting cell-free DNA (cfDNA) and circulating proteins have been
tested for pan-cancer detection. Oncofetal chondroitin sulfate (ofCS), which distinctively …
tested for pan-cancer detection. Oncofetal chondroitin sulfate (ofCS), which distinctively …
Glycosaminoglycans in cancer therapy
R Wieboldt, H Läubli - American Journal of Physiology-Cell …, 2022 - journals.physiology.org
Glycosaminoglycans (GAGs) are an important component of the tumor microenvironment
(TME). GAGs can interact with a variety of binding partners and thereby influence cancer …
(TME). GAGs can interact with a variety of binding partners and thereby influence cancer …
Indications of persistent glycocalyx damage in convalescent COVID-19 patients: a prospective multicenter study and hypothesis
R Vollenberg, PR Tepasse, K Ochs, M Floer, M Strauss… - Viruses, 2021 - mdpi.com
The COVID-19 pandemic is caused by the SARS CoV-2 virus and can lead to severe lung
damage and hyperinflammation. In the context of COVID-19 infection, inflammation-induced …
damage and hyperinflammation. In the context of COVID-19 infection, inflammation-induced …
Network-Pharmacology-Based Study on Active Phytochemicals and Molecular Mechanism of Cnidium monnieri in Treating Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is a malignancy with a high mortality rate globally. For
thousands of years, Cnidium monnieri has been used to treat human ailments and is …
thousands of years, Cnidium monnieri has been used to treat human ailments and is …
Mucin glycans: A target for cancer therapy
L Sun, Y Zhang, W Li, J Zhang, Y Zhang - Molecules, 2023 - mdpi.com
Mucin glycans are an important component of the mucus barrier and a vital defence against
physical and chemical damage as well as pathogens. There are 20 mucins in the human …
physical and chemical damage as well as pathogens. There are 20 mucins in the human …