Insight into the key points of preeclampsia pathophysiology: uterine artery remodeling and the role of microRNAs

K Pankiewicz, A Fijałkowska, T Issat… - International journal of …, 2021 - mdpi.com
Preeclampsia affects about 3–8% of all pregnancies. It represents a complex and
multifaceted syndrome with at least several potential pathways leading to the development …

Prenatal hypoxia and placental oxidative stress: linkages to developmental origins of cardiovascular disease

MM Aljunaidy, JS Morton… - American Journal of …, 2017 - journals.physiology.org
Intrauterine growth restriction (IUGR, a pregnancy complication where the fetus does not
reach its genetic growth potential) is a leading cause of fetal morbidity and mortality with a …

The free radical diseases of prematurity: from cellular mechanisms to bedside

S Perrone, A Santacroce, M Longini… - Oxidative medicine …, 2018 - Wiley Online Library
During the perinatal period, free radicals (FRs) are involved in several physiological roles
such as the cellular responses to noxia, the defense against infectious agents, the regulation …

Genetic background of fetal growth restriction

BA Nowakowska, K Pankiewicz, U Nowacka… - International Journal of …, 2021 - mdpi.com
Fetal growth restriction (FGR) is one of the most formidable challenges in present-day
antenatal care. Pathological fetal growth is a well-known factor of not only in utero demise in …

Increased autophagy in placentas of intrauterine growth-restricted pregnancies

TH Hung, SF Chen, LM Lo, MJ Li, YL Yeh, TT Hsieh - PloS one, 2012 - journals.plos.org
Background Unexplained intrauterine growth restriction (IUGR) may be a consequence of
placental insufficiency; however, its etiology is not fully understood. We surmised that …

The roles of free iron, heme, haemoglobin, and the scavenger proteins haemopexin and alpha‐1‐microglobulin in preeclampsia and fetal growth restriction

L Erlandsson, Z Masoumi, LR Hansson… - Journal of internal …, 2021 - Wiley Online Library
Background Preeclampsia (PE) is a complex pregnancy syndrome characterised by
maternal hypertension and organ damage after 20 weeks of gestation and is associated with …

Impact of the ACOG guideline regarding low-dose aspirin for prevention of superimposed preeclampsia in women with chronic hypertension

C Banala, S Moreno, Y Cruz, RC Boelig… - American journal of …, 2020 - Elsevier
Background Patients with chronic hypertension are at increased risk for superimposed
preeclampsia. The 2016 American College of Obstetricians and Gynecologists guideline …

Biomarkers of oxidative stress in the fetus and in the newborn

S Perrone, E Laschi, G Buonocore - Free Radical Biology and Medicine, 2019 - Elsevier
The dynamic field of perinatology entails ever-increasing search for molecular mechanisms
of neonatal diseases, especially in the domain of fetal growth and neurodevelopmental …

[HTML][HTML] The association between urinary glyphosate and aminomethyl phosphonic acid with biomarkers of oxidative stress among pregnant women in the PROTECT …

JL Eaton, AL Cathey, JA Fernandez, DJ Watkins… - Ecotoxicology and …, 2022 - Elsevier
Background Glyphosate is a widely used herbicide in global agriculture. Glyphosate and its
primary environmental degradate, aminomethyl phosphonic acid (AMPA), have been shown …

Pathophysiology of Pre-Eclampsia—Two Theories of the Development of the Disease

J Kornacki, O Olejniczak, R Sibiak, P Gutaj… - International Journal of …, 2023 - mdpi.com
Pre-eclampsia (PE) continues to be a leading cause of maternal and fetal mortality and
morbidity. While substantial progress has been made in understanding the …