Long non-coding RNAs and rheumatoid arthritis: Pathogenesis and clinical implications
Long non-coding RNAs (lncRNAs) are a class of noncoding RNAs with a length larger than
200 nucleotides that participate in various diseases and biological processes as they can …
200 nucleotides that participate in various diseases and biological processes as they can …
Apoptosis induction of fibroblast-like synoviocytes is an important molecular-mechanism for herbal medicine along with its active components in treating rheumatoid …
Rheumatoid arthritis (RA) is a known chronic autoimmune disease can cause joint deformity
and even loss of joint function. Fibroblast-like synoviocytes (FLS), one of the main cell types …
and even loss of joint function. Fibroblast-like synoviocytes (FLS), one of the main cell types …
Triptolide inhibits cell growth and inflammatory response of fibroblast-like synoviocytes by modulating hsa-circ-0003353/microRNA-31-5p/CDK1 axis in rheumatoid …
J Wen, J Liu, L Wan, L Xin, J Guo, Y Sun… - International …, 2022 - Elsevier
Triptolide (TPL) is an active component derived from Tripterygium wilfordii Hook F (TwHF)
with therapeutic potential for rheumatoid arthritis (RA). However, the underlying mechanism …
with therapeutic potential for rheumatoid arthritis (RA). However, the underlying mechanism …
Therapeutic potential of extracellular vesicle‐associated long noncoding RNA
Both extracellular vesicles (EVs) and long noncoding RNAs (lncRNAs) have been
increasingly investigated as biomarkers, pathophysiological mediators, and potential …
increasingly investigated as biomarkers, pathophysiological mediators, and potential …
LncRNA GAS5 alleviates rheumatoid arthritis through regulating miR-222-3p/Sirt1 signalling axis
Z Yang, SD Lin, F Zhan, Y Liu, YW Zhan - Autoimmunity, 2021 - Taylor & Francis
Introduction Rheumatoid arthritis (RA) is an autoimmune disease that affects millions of
people. Fibroblast-like synoviocytes (FLSs) located in rheumatoid panni play a pivotal role in …
people. Fibroblast-like synoviocytes (FLSs) located in rheumatoid panni play a pivotal role in …
Long noncoding RNA/circular RNA regulates competitive endogenous RNA networks in rheumatoid arthritis: molecular mechanisms and traditional Chinese medicine …
J Wen, J Liu, L Wan, F Wang - Annals of Medicine, 2023 - Taylor & Francis
Rheumatoid arthritis (RA) is a systemic and autoimmune disease that is mainly featured
abnormal fibroblast-like synoviocyte (FLS) proliferation and inflammatory cell infiltration …
abnormal fibroblast-like synoviocyte (FLS) proliferation and inflammatory cell infiltration …
Dysregulation of lncRNAs in rheumatoid arthritis: biomarkers, pathogenesis and potential therapeutic targets
C Miao, L Bai, Y Yang, J Huang - Frontiers in pharmacology, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic autoimmune disease of unknown etiology, mainly
manifested by persistent abnormal proliferation of fibroblast-like synoviocytes (FLSs) …
manifested by persistent abnormal proliferation of fibroblast-like synoviocytes (FLSs) …
Triptolide promotes the apoptosis and attenuates the inflammation of fibroblast‐like synoviocytes in rheumatoid arthritis by down‐regulating lncRNA …
J Wen, J Liu, X Wang, J Wang - Phytotherapy Research, 2021 - Wiley Online Library
Rheumatoid arthritis (RA), recognized as a common chronic autoimmune disease, is
characterized by the excessive proliferation and inflammatory infiltration of fibroblast‐like …
characterized by the excessive proliferation and inflammatory infiltration of fibroblast‐like …
Therapeutic Effects of (5R)-5-Hydroxytriptolide on Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via lncRNA WAKMAR2/miR-4478/E2F1/p53 Axis
Rheumatoid arthritis (RA) is an autoimmune disease. Fibroblast-like synoviocytes (FLS)
serve a major role in synovial hyperplasia and inflammation in RA.(5R)-5-hydroxytriptolide …
serve a major role in synovial hyperplasia and inflammation in RA.(5R)-5-hydroxytriptolide …
[HTML][HTML] Dysregulation of non-coding RNAs in rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic inflammatory disorder that is associated with both
genetic and environmental factors. Dysregulation of the immune response is the main …
genetic and environmental factors. Dysregulation of the immune response is the main …