Challenges and strategies for developing efficacious and long-lasting malaria vaccines

JG Beeson, L Kurtovic, C Dobaño, DH Opi… - Science translational …, 2019 - science.org
Although there has been major recent progress in malaria vaccine development, substantial
challenges remain for achieving highly efficacious and durable vaccines against …

Blood groups and malaria: fresh insights into pathogenesis and identification of targets for intervention

JA Rowe, DH Opi, TN Williams - Current opinion in hematology, 2009 - journals.lww.com
Blood groups and malaria: fresh insights into pathogenesis a... : Current Opinion in Hematology
Blood groups and malaria: fresh insights into pathogenesis and identification of targets for …

Malaria eradication and elimination: views on how to translate a vision into reality

M Tanner, B Greenwood, CJM Whitty, EK Ansah… - BMC medicine, 2015 - Springer
Although global efforts in the past decade have halved the number of deaths due to malaria,
there are still an estimated 219 million cases of malaria a year, causing more than half a …

Duffy Negative Antigen Is No Longer a Barrier to Plasmodium vivax – Molecular Evidences from the African West Coast (Angola and Equatorial Guinea)

C Mendes, F Dias, J Figueiredo, VG Mora… - PLoS neglected …, 2011 - journals.plos.org
Background Plasmodium vivax shows a small prevalence in West and Central Africa due to
the high prevalence of Duffy negative people. However, Duffy negative individuals infected …

A reliable ex vivo invasion assay of human reticulocytes by Plasmodium vivax

B Russell, R Suwanarusk, C Borlon… - Blood, The Journal …, 2011 - ashpublications.org
Currently, there are no reliable RBC invasion assays to guide the discovery of vaccines
against Plasmodium vivax, the most prevalent malaria parasite in Asia and South America …

Red Blood Cell Invasion by Plasmodium vivax: Structural Basis for DBP Engagement of DARC

JD Batchelor, BM Malpede, NS Omattage… - PLoS …, 2014 - journals.plos.org
Plasmodium parasites use specialized ligands which bind to red blood cell (RBC) receptors
during invasion. Defining the mechanism of receptor recognition is essential for the design …

Plasmodium vivax Biology: Insights Provided by Genomics, Transcriptomics and Proteomics

C Bourgard, L Albrecht, ACAV Kayano… - Frontiers in cellular …, 2018 - frontiersin.org
During the last decade, the vast omics field has revolutionized biological research,
especially the genomics, transcriptomics and proteomics branches, as technological tools …

Immunological markers of Plasmodium vivaxexposure and immunity: a systematic review and meta-analysis

JC Cutts, R Powell, PA Agius, JG Beeson, JA Simpson… - BMC medicine, 2014 - Springer
Abstract Background Identifying Plasmodium vivax antigen-specific antibodies associated
with P. vivax infection and protective immunity is key to the development of serosurveillance …

MicroRNAs in the host-apicomplexan parasites interactions: a review of immunopathological aspects

CC Judice, C Bourgard, ACAV Kayano… - Frontiers in cellular …, 2016 - frontiersin.org
MicroRNAs (miRNAs), a class of small non-coding regulatory RNAs, have been detected in
a variety of organisms ranging from ancient unicellular eukaryotes to mammals. They have …

The origin of mass

P Boyle, MI Buchoff, N Christ, T Izubuchi… - Proceedings of the …, 2013 - dl.acm.org
The origin of mass is one of the deepest mysteries in science. Neutrons and protons, which
account for almost all visible mass in the Universe, emerged from a primordial plasma …