Bismuth as a relatively non-toxic and inexpensive metal with exceptional properties has
numerous biomedical applications. Bismuth-based compounds are used extensively as …

Metallic radionuclides possess a variety of half-lives, emission types, energies, and
branching ratios, making it possible to apply them as diagnostic and/or therapeutic agents …

In contrast to external high energy photon or proton therapy, targeted radionuclide therapy
(TRNT) is a systemic cancer treatment allowing targeted irradiation of a primary tumor and …

Rationale: Physiologically based pharmacokinetic (PBPK) and population pharmacokinetic
(PK) modelling approaches are widely accepted in non-radiopharmaceutical drug …

This review article explores the dynamic field of radiopharmaceuticals, where innovative
developments arise from combining radioisotopes and pharmaceuticals, opening up …

Background Gallium-68 labeled synthetic somatostatin analogs for PET/CT imaging are the
current gold standard for somatostatin receptor imaging in neuroendocrine tumor patients …

The production of reactor-based medical isotopes is fragile, which has meant supply
shortages from time to time. This paper reviews alternative production methods in the form of …

Background: Radiolabeled somatostatin analogues (eg [68 Ga] Ga-DOTATATE and [177 Lu]
Lu-DOTATATE) have been used to diagnose, monitor, and treat neuroendocrine tumour …

The high energy of α emitters, and the strong linear energy transfer that goes along with it,
lead to very efficient cell killing through DNA damage. Moreover, the degree of oxygenation …

Fibroblast activation protein (FAP) is closely related to central nervous system diseases such
as stroke and brain tumors, but PET tracers that can be used for brain imaging have not …