The V protein in oncolytic Newcastle disease virus promotes HepG2 hepatoma cell proliferation at the single-cell level

Z Chu, S Yang, Q Li, J Shang, Z Ren, F Ren - BMC cancer, 2023 - Springer
Background Newcastle disease virus (NDV) is an oncolytic virus that can inhibit cancer cell
proliferation and kill cancer cells. The NDV nonstructural V protein can regulate viral …

Signaling pathways triggering therapeutic hydrogels in promoting chronic wound healing

F Chen, P Wu, H Zhang, G Sun - Macromolecular Bioscience, 2024 - Wiley Online Library
In recent years, there has been a significant increase in the prevalence of chronic wounds,
such as pressure ulcers, diabetic foot ulcers, and venous ulcers of the lower extremities. The …

The Multifaceted Role of Human Dickkopf-3 (DKK-3) in Development, Immune Modulation and Cancer

J Mourtada, C Thibaudeau, B Wasylyk, AC Jung - Cells, 2023 - mdpi.com
The human Dickkopf (DKK) family includes four main secreted proteins, DKK-1, DKK-2, DKK-
3, and DKK-4, as well as the DKK-3 related protein soggy (Sgy-1 or DKKL1). These …

Wnt Signaling and Therapeutic Resistance in Castration-Resistant Prostate Cancer

C Kishore, X Zi - Current pharmacology reports, 2023 - Springer
Abstract Purpose of Review Castration-resistant prostate cancer (CRPC) is a lethal form of
prostate cancer (PCa) due to the development of resistance to androgen deprivation therapy …

Identification and characterization of long non-coding RNA (lncRNA) in cypermethrin and chlorpyrifos exposed zebrafish (Danio rerio) brain

S Özdemir, Ş Aydın, BB Laçin, H Arslan - Chemosphere, 2023 - Elsevier
Pesticides, such as cypermethrin (CYP) and chlorpyrifos (CPF), are widely used around the
world and are known to cause toxicological effects in the brains of fish and other non-target …

Extracellular vesicles-coupled miRNAs from oviduct and uterus modulate signaling pathways related to lipid metabolism and bovine early embryo development

R Mazzarella, K Cañón-Beltrán, YN Cajas… - Journal of Animal …, 2024 - Springer
Abstract Background Extracellular vesicles (EVs) present in oviductal (OF) and uterine fluid
(UF) have been shown to enhance bovine embryo quality during in vitro culture by reducing …

Exploring the Key Signaling Pathways and ncRNAs in Colorectal Cancer

YJ Lee, WR Kim, EG Park, DH Lee, J Kim… - International Journal of …, 2024 - mdpi.com
Colorectal cancer (CRC) is the third most prevalent cancer to be diagnosed, and it has a
substantial mortality rate. Despite numerous studies being conducted on CRC, it remains a …

The role of paxillin aberrant expression in cancer and its potential as a target for cancer therapy

W Liu, X Huang, W Luo, X Liu, W Chen - International Journal of …, 2023 - mdpi.com
Paxillin is a multi-domain adaptor protein. As an important member of focal adhesion (FA)
and a participant in regulating cell movement, paxillin plays an important role in …

Molecular mechanisms of microRNA-216a during tumor progression

AA Hamidi, N Taghehchian, AS Zangouei… - Cancer Cell …, 2023 - Springer
MicroRNAs (miRNAs) as the members of non-coding RNAs family are involved in post-
transcriptional regulation by translational inhibiting or mRNA degradation. They have a …

LncRNA12097. 1 contributes to endometrial cell growth by enhancing YES1 activating β-catenin via sponging miR-145-5p

X Li, K Li, K Deng, Z Liu, X Huang, J Guo… - International Journal of …, 2024 - Elsevier
Despite previous investigations elucidating the regulatory mechanisms of long non-coding
RNAs (lncRNAs) in endometrial function and reproductive disorders, the precise pathways …