Pediatric retinal vascular disorders: From translational sciences to clinical practice

P Maitra - Saudi Journal of Ophthalmology, 2023 - journals.lww.com
Pediatric retinal vascular diseases are a spectrum with overlapping phenotypes and related
genes. Retinal vascular development is biphasic. Vasculogenesis is responsible for the …

SFRP4 protein expression is reduced in high grade astrocytomas which is not caused by the methylation of its promoter

A Kafka, N Pecina-Slaus, D Drmic… - Frontiers in Molecular …, 2024 - frontiersin.org
Introduction: Epigenetics play a vital role in stratifying CNS tumors and gliomas. The
importance of studying Secreted frizzled-related protein 4 (SFRP4) in gliomas is to improve …

WNTA5-mediated miR-374a-5p regulates vascular smooth muscle cell phenotype transformation and M1 macrophage polarization impacting intracranial aneurysm …

Z Li, J Huang, L Yang, X Li, W Li - Scientific Reports, 2024 - nature.com
Abstract miR-374a-5p expression and localization in intracranial aneurysm (IA) tissues were
detected, and its correlation with vascular smooth muscle cells (VSMCs) and macrophage …

Administration of stem cells against cardiovascular diseases with a focus on molecular mechanisms: Current knowledge and prospects

M Karimian, N Nouri, LV Ghasemi, AH Mohammadi… - Tissue and Cell, 2023 - Elsevier
Cardiovascular diseases (CVDs) are a serious global concern for public and human health.
Despite the emergence of significant therapeutic advances, it is still the leading cause of …

From Youthful Vigor to Aging Decline: Unravelling the Intrinsic and Extrinsic Determinants of Hippocampal Neural Stem Cell Aging

P Jiménez Peinado, A Urbach - Cells, 2023 - mdpi.com
Since Joseph Altman published his pioneering work demonstrating neurogenesis in the
hippocampus of adult rats, the number of publications in this field increased exponentially …

Diverse Functions of MiR-425 in Human Cancer

Z Wang, W Xie, H Guan - DNA and Cell Biology, 2023 - liebertpub.com
miRNAs are a type of small endogenous noncoding RNA composed of 20–22 nucleotides
that can regulate gene expression by targeting the 3′ untranslated region of mRNA. Many …

Wnt Signaling Activation in Gingival Epithelial Cells and Macrophages of Experimental Periodontitis

Y Chen, Y Hu - Dentistry Journal, 2023 - mdpi.com
Objective: Wingless/integrated (Wnt) signaling plays critical roles in maintaining
environmental homeostasis and is also involved in the pathogenesis of inflammatory …

A literature review on signaling pathways of cervical cancer cell death-apoptosis induced by Traditional Chinese Medicine

C Peng, Y Wang, Y Guo, J Li, F Liu, Y Fu, Y Yu… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Cervical cancer (CC) is a potentially lethal disorder that
can have serious consequences for a woman's health. Because early symptoms are …

Effects of Physical Cues on Stem Cell-Derived Extracellular Vesicles toward Neuropathy Applications

D Berry, J Ene, A Nathani, M Singh, Y Li, C Zeng - Biomedicines, 2024 - mdpi.com
The peripheral nervous system undergoes sufficient stress when affected by diabetic
conditions, chemotherapeutic drugs, and personal injury. Consequently, peripheral …

Comprehensive analysis of mitochondria-related genes indicates that PPP2R2B is a novel biomarker and promotes the progression of bladder cancer via Wnt …

D Shen, S Kang - Biology direct, 2024 - Springer
Bladder cancer (BC) is the fourth and tenth most common malignancy in men and women
worldwide, respectively. The complexity of the molecular biological mechanism behind BC is …