Microfibrillar-associated protein 2 (MFAP2), a component of the extracellular matrix, is
important in controlling growth factor signal transduction. Recent studies have shown that …

Background Acute myeloid leukaemia (AML) is a disease of the haematopoietic stem cells
(HSCs) that is characterised by the uncontrolled proliferation and impaired differentiation of …

Background/purpose Dental pulp stem cells (DPSCs) have demonstrated significant
potential for neuroregeneration. However, a full understanding of the specific mechanism …

Background Clear cell renal cell carcinoma (RCC) is the most common subtype of RCC.
Although targeted therapy can provide superior treatment outcomes, it is prone to drug …

Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs) are crucially implicated in the
cancer progression. The current study intends to excavate and clarify the mechanisms of the …

The inference of cell–cell communication is important, as it unveils the intricate cellular
behaviors at the molecular level, providing crucial insights essential for understanding …

The WNT inhibitory protein DKK1 has been shown to regulate the development of the
preimplantation embryo to the blastocyst stage. In cattle, DKK1 increases the number of …

In the central nervous system, thrombin-mediated activation of protease-activated receptors
(PARs) results in neuroinflammation and increased vascular permeability. These events …

Transposons are parasitic genetic elements that frequently hijack vital cellular processes of
their host. HMGXB4 is a known Wnt signaling-regulating HMG-box protein, previously …

Chronic kidney disease (CKD) is a serious public health problem. Due to a high variability in
the speed of CKD progression to end-stage renal disease (ESRD) and the critical …