The inference of cell–cell communication is important, as it unveils the intricate cellular
behaviors at the molecular level, providing crucial insights essential for understanding …

The WNT inhibitory protein DKK1 has been shown to regulate the development of the
preimplantation embryo to the blastocyst stage. In cattle, DKK1 increases the number of …

In the central nervous system, thrombin-mediated activation of protease-activated receptors
(PARs) results in neuroinflammation and increased vascular permeability. These events …

Transposons are parasitic genetic elements that frequently hijack vital cellular processes of
their host. HMGXB4 is a known Wnt signaling-regulating HMG-box protein, previously …

Chronic kidney disease (CKD) is a serious public health problem. Due to a high variability in
the speed of CKD progression to end-stage renal disease (ESRD) and the critical …

The present work focused on investigating the role of the altered expression of complement
C1s in proliferation and apoptosis of esophageal squamous cell carcinoma (ESCC) cells …

Pulmonary arterial hypertension (PAH) is a chronic, progressive and rapidly fatal disease
with a poor prognosis, high mortality rate and lack of curative treatment options [1], defined …

Ischemic stroke remains a major cause of disability and death. Kaempferol (Kae) is a
neuroprotective flavonoid compound. Thus, this study aimed to explore the impact of Kae on …

One of the key goals in studying the molecular and genetic basis of many pathologies is to
find triggers that could positively influence the incidence of age-dependent diseases and the …

本文深入研究了骨质疏松症的定义和流行病学特征, 并综述了Wnt 信号通路在维护骨骼健康方面
的重要作用. Wnt 信号通路通过促进骨细胞分化, 骨基质合成以及抑制骨吸收等机制 …