Assessing respiratory mechanics and muscle function is critical for both clinical practice and
research purposes. Several methodological developments over the past two decades have …

The standard respiratory function test for case detection of chronic obstructive pulmonary
disease (COPD) is spirometry. The criterion for diagnosis defined in guidelines is based on …

Complete surgical resection is the most effective curative treatment for lung cancer.
However, many patients with lung cancer also have severe COPD which increases their risk …

For over 150 years, bronchoscopy, especially flexible bronchoscopy, has been a mainstay
for airway inspection, the diagnosis of airway lesions, therapeutic aspiration of airway …

Background Many studies show a link between forced expiratory volume in 1 s (FEV1) and
survival in the general population and this has been interpreted as a link between airway …

Introduction Modified-risk tobacco products are expected to reduce exposure to harmful and
potentially harmful constituents of cigarette smoke, and ultimately reduce the health burden …

The main complaint of patients with chronic obstructive pulmonary disease (COPD) is
shortness of breath with exercise, that is usually progressive. The principal mechanism that …

Pulmonary function testing is often considered the basis for diagnosis in many categories of
pulmonary disease. Although most of the testing methodologies are well established and …

The natural history of lung hyperinflation in patients with airway obstruction is unknown. In
particular, little information exists about the extent of air trapping and its reversibility to …

Spirometry is the current gold standard for diagnosing and monitoring the progression of
Chronic Obstructive Pulmonary Disease (COPD). However, many current and former …