The study of biological systems in a holistic manner (systems biology) is increasingly being
viewed as a necessity to provide qualitative and quantitative descriptions of the emergent …

In the post-genomic era, several profiling tools have been developed to provide a more
comprehensive picture of tumour development and progression. The global analysis of …

In this review, the background to the approach known as metabonomics is provided, giving a
brief historical perspective and summarizing the analytical and statistical techniques used …

Clinical trials of new cancer drugs should ideally include measurements of parameters such
as molecular target expression, pharmacokinetic (PK) behavior, and pharmacodynamic (PD) …

To date most global approaches to functional genomics have centred on genomics,
transcriptomics and proteomics. However, since a number of high-profile publications …

Colorectal cancer (CRC) is a major cause of morbidity and mortality in developed countries.
Despite operative advances and the widespread adoption of combined-modality treatment …

The collection of global metabolic data and their interpretation (both spectral and
biochemical) using modern spectroscopic techniques and appropriate statistical …

Breast cancer is the most common cancer in women worldwide, and the development of
new technologies for better understanding of the molecular changes involved in breast …

NMR spectroscopy was used to identify and quantify compounds in extracts prepared from
mature trophozoite‐stage Plasmodium falciparum parasites isolated by saponin …

One of the central hallmarks of cancer is the rapid and infinite cellular proliferation. In order
to cope with increased requirement for building blocks and energy, cancer cells develop …