Nuclear Magnetic Resonance (MR) based imaging has become an integrated domain in
today's oncology research and clinical management of cancer patients. MR is a unique …

Background Loss of the endosulfatase HSulf-1 is common in ovarian cancer, upregulates
heparin binding growth factor signaling and potentiates tumorigenesis and angiogenesis …

BACKGROUND: Improved non-invasive imaging biomarkers of treatment response
contribute to optimising cancer management and metabolites detected by proton magnetic …

The measurement of water diffusion by diffusion‐weighted MRI (DWI) in vivo offers a non‐
invasive method for assessing tissue responses to anti‐cancer therapies. The pathway of …

High-resolution magic angle spinning (HRMAS) is the combined application of high-
resolution NMR experiments with dipolar-and susceptibility-reducing sample rotation to …

Glioblastoma continues to be an invariably fatal malignancy. The established approach for
understanding the biology of these aggressive tumors in an effort to identify novel molecular …

High-resolution magic-angle spinning (HR-MAS) NMR was developed in late 1990s, and it
has evolved quickly for the study of a variety of biological matrixes. Recently, it has been …

Abstract Changes in the concentrations of choline‐containing metabolites (CCM) have been
implicated in both cell proliferation and death processes. In this study, high‐resolution magic …

Choline and the related compounds phosphocholine (PC) and glycerophosphocholine
(GPC) are considered to be important metabolites in oncology. Past studies have …

Tracking metabolic profiles has the potential to reveal crucial enzymatic steps that could be
targeted in the drug discovery process. It is of special importance for various types of cancer …