Dopamine in Parkinson's disease

S Latif, M Jahangeer, DM Razia, M Ashiq, A Ghaffar… - Clinica chimica acta, 2021 - Elsevier
Parkinson's disease is a neurodegenerative disease caused by the death of neurons, ie,
cells critical to the production of dopamine, an important neurotransmitter in the brain. Here …

[HTML][HTML] Risperidone induced hyperprolactinemia: from basic to clinical studies

M Stojkovic, B Radmanovic, M Jovanovic… - Frontiers in …, 2022 - frontiersin.org
Risperidone is one of the most commonly used antipsychotics (AP), due to its safety and
efficacy in reducing psychotic symptoms. Despite the favorable side effect profile, the …

Adverse effects of early-life stress: focus on the rodent neuroendocrine system

SH Lee, EM Jung - Neural Regeneration Research, 2023 - journals.lww.com
Early-life stress is associated with a high prevalence of mental illnesses such as post-
traumatic stress disorders, attention-deficit/hyperactivity disorder, schizophrenia, and anxiety …

Endocannabinoid modulation of dopamine release during reward seeking, interval timing, and avoidance

TJ Everett, DM Gomez, LR Hamilton… - Progress in Neuro …, 2021 - Elsevier
Endocannabinoids (eCBs) are neuromodulators that influence a wide range of neural
systems and behaviors. In the current review, we describe our recent research showing how …

[HTML][HTML] Dopamine increases the intrinsic excitability of parvalbumin-expressing fast-spiking cells in the piriform cortex

Y Potts, JM Bekkers - Frontiers in Cellular Neuroscience, 2022 - frontiersin.org
The piriform cortex (PCx) is essential for the adaptive processing of olfactory information.
Neuromodulatory systems, including those utilizing serotonin, acetylcholine, noradrenaline …

The dopamine membrane transporter plays an active modulatory role in synaptic dopamine homeostasis

R Formisano, KD Rosikon, A Singh… - Journal of …, 2022 - Wiley Online Library
Modulatory mechanisms of neurotransmitter release and clearance are highly controlled
processes whose finely tuned regulation is critical for functioning of the nervous system …

Off-target effects in transgenic mice: characterization of dopamine transporter (DAT)-Cre transgenic mouse lines exposes multiple non-dopaminergic neuronal clusters …

M Papathanou, S Dumas, H Pettersson, L Olson… - Eneuro, 2019 - eneuro.org
Transgenic mouse lines are instrumental in our attempt to understand brain function.
Promoters driving transgenic expression of the gene encoding Cre recombinase are crucial …

[HTML][HTML] Physiology, hypothalamus

Z Shahid, E Asuka, G Singh - 2018 - europepmc.org
The hypothalamus is the region in the ventral brain which coordinates the endocrine system.
It receives many signals from various regions of the brain and in return, releases both …

Trpc5 deficiency causes hypoprolactinemia and altered function of oscillatory dopamine neurons in the arcuate nucleus

T Blum, A Moreno-Pérez, M Pyrski… - Proceedings of the …, 2019 - National Acad Sciences
Dopamine neurons of the hypothalamic arcuate nucleus (ARC) tonically inhibit the release
of the protein hormone prolactin from lactotropic cells in the anterior pituitary gland and thus …

Ghrelin amplifies the nicotine-induced release of dopamine in the bed nucleus of stria terminalis (BNST)

J Ayman, M Palotai, R Dochnal, Z Bagosi - Biomedicines, 2023 - mdpi.com
Ghrelin is an orexigenic neuropeptide that is known for stimulating the release of growth
hormone (GH) and appetite. In addition, ghrelin has been implicated in addiction to drugs …