Dendrimers: a new race of pharmaceutical nanocarriers

P Mittal, A Saharan, R Verma… - BioMed Research …, 2021 - Wiley Online Library
Dendrimers are nanosized, symmetrical molecules in which a small atom or group of atoms
is surrounded by the symmetric branches known as dendrons. The structure of dendrimers …

Recent advances in nanoparticle-based targeted drug-delivery systems against cancer and role of tumor microenvironment

UA Ashfaq, M Riaz, E Yasmeen… - Critical Reviews™ in …, 2017 - dl.begellhouse.com
Cancer is one of the major causes of death worldwide. The silent activation of cellular factors
responsible for deviation from normal regulatory pathways leads to the development of …

Bioapplications of poly (amidoamine)(PAMAM) dendrimers in nanomedicine

N Taghavi Pourianazar, P Mutlu, U Gunduz - Journal of Nanoparticle …, 2014 - Springer
Abstract Poly (amidoamine)(PAMAM) dendrimers are a novel class of spherical, well-
designed branching polymers with interior cavities and abundant terminal groups on the …

Synthesis and characterization of novel 99mTc-DGC nano-complexes for improvement of heart diagnostic

MS Ardestani, A Bitarafan-Rajabi… - Bioorganic …, 2020 - Elsevier
In this research, early diagnosis of cardiovascular diseases can reduce their mortality and
burden. In our study, we developed a new nano-agent, 99m Tc-Dendrimer Glyco Conjugate …

Intrinsically fluorescent PAMAM dendrimer as gene carrier and nanoprobe for nucleic acids delivery: bioimaging and transfection study

YJ Tsai, CC Hu, CC Chu, T Imae - Biomacromolecules, 2011 - ACS Publications
This study successfully evaluated gene delivery and transfection toward rat C6 glioma cell
lines mediated by intrinsic blue fluorescent poly (amido amine)(PAMAM) dendrimer. We …

PEG‐Citrate dendrimer second generation: is this a good carrier for imaging agents In Vitro and In Vivo ?

P Mohammadzadeh, M Shafiee Ardestani… - IET …, 2019 - Wiley Online Library
While cancer is the leading cause of human's deaths worldwide, finding an imaging agent
which can detect cancer tumours is needed for cancer diagnosis. In the present study, PEG …

Understanding effects of PAMAM dendrimer size and surface chemistry on serum protein binding with discrete molecular dynamics simulations

B Wang, Y Sun, TP Davis, PC Ke, Y Wu… - … sustainable chemistry & …, 2018 - ACS Publications
Polyamidoamine (PAMAM) dendrimers, a class of polymeric nanoparticles (NPs) with highly
controllable sizes and surface chemistry, are promising candidates for many biomedical …

[HTML][HTML] Dendrimers: advancements and potential applications in cancer diagnosis and treatment—an overview

A Crintea, AC Motofelea, AS Șovrea, AM Constantin… - Pharmaceutics, 2023 - mdpi.com
Cancer is a leading cause of death worldwide, and the main treatment methods for this
condition are surgery, chemotherapy, and radiotherapy. These treatment methods are …

Technetium-99m chelator-free radiolabeling of specific glutamine tumor imaging nanoprobe: in vitro and in vivo evaluations

SM Ghoreishi, A Khalaj, O Sabzevari… - International Journal …, 2018 - Taylor & Francis
Introduction Nowadays, molecular imaging radiopharmaceuticals', nanoparticles', and/or
small-molecule biomarkers' applications are increasing rapidly worldwide. Thus …

[PDF][PDF] S, ovrea, AS; Constantin, A

A Crintea, AC Motofelea - cancer, 2023 - academia.edu
Cancer is a leading cause of death worldwide, and the main treatment methods for this
condition are surgery, chemotherapy, and radiotherapy. These treatment methods are …