The matrix in cancer
TR Cox - Nature Reviews Cancer, 2021 - nature.com
The extracellular matrix is a fundamental, core component of all tissues and organs, and is
essential for the existence of multicellular organisms. From the earliest stages of organism …
essential for the existence of multicellular organisms. From the earliest stages of organism …
FGF/FGFR signaling in health and disease
Y Xie, N Su, J Yang, Q Tan, S Huang, M Jin… - Signal transduction and …, 2020 - nature.com
Growing evidences suggest that the fibroblast growth factor/FGF receptor (FGF/FGFR)
signaling has crucial roles in a multitude of processes during embryonic development and …
signaling has crucial roles in a multitude of processes during embryonic development and …
The role of myofibroblasts in physiological and pathological tissue repair
Myofibroblasts are the construction workers of wound healing and repair damaged tissues
by producing and organizing collagen/extracellular matrix (ECM) into scar tissue. Scar tissue …
by producing and organizing collagen/extracellular matrix (ECM) into scar tissue. Scar tissue …
Targeting TGFβ signal transduction for cancer therapy
S Liu, J Ren, P Ten Dijke - Signal transduction and targeted therapy, 2021 - nature.com
Transforming growth factor-β (TGFβ) family members are structurally and functionally related
cytokines that have diverse effects on the regulation of cell fate during embryonic …
cytokines that have diverse effects on the regulation of cell fate during embryonic …
Cell adhesion in cancer: Beyond the migration of single cells
Homeostasis in healthy tissues strongly relies on cell-to-cell adhesion and cell-to-
extracellular matrix interactions. For instance, normal epithelial cells maintain tissue …
extracellular matrix interactions. For instance, normal epithelial cells maintain tissue …
TGF-β1–a truly transforming growth factor in fibrosis and immunity
M Lodyga, B Hinz - Seminars in cell & developmental biology, 2020 - Elsevier
Abstract 'Jack of all trades, master of everything'is a fair label for transforming growth factor
β1 (TGF-β)–a cytokine that controls our life at many levels. In the adult organism, TGF-β1 is …
β1 (TGF-β)–a cytokine that controls our life at many levels. In the adult organism, TGF-β1 is …
The extracellular matrix in development
DAC Walma, KM Yamada - Development, 2020 - journals.biologists.com
As the crucial non-cellular component of tissues, the extracellular matrix (ECM) provides
both physical support and signaling regulation to cells. Some ECM molecules provide a …
both physical support and signaling regulation to cells. Some ECM molecules provide a …
Static and dynamic: evolving biomaterial mechanical properties to control cellular mechanotransduction
The extracellular matrix (ECM) is a highly dynamic system that constantly offers physical,
biological, and chemical signals to embraced cells. Increasing evidence suggests that …
biological, and chemical signals to embraced cells. Increasing evidence suggests that …
[HTML][HTML] Integrins in cancer: Emerging mechanisms and therapeutic opportunities
F Liu, Q Wu, Z Dong, K Liu - Pharmacology & therapeutics, 2023 - Elsevier
Integrins are vital surface adhesion receptors that mediate interactions between the
extracellular matrix (ECM) and cells and are essential for cell migration and the …
extracellular matrix (ECM) and cells and are essential for cell migration and the …
Into the tissues: Extracellular matrix and its artificial substitutes: Cell signalling mechanisms
A Bandzerewicz, A Gadomska-Gajadhur - Cells, 2022 - mdpi.com
The existence of orderly structures, such as tissues and organs is made possible by cell
adhesion, ie, the process by which cells attach to neighbouring cells and a supporting …
adhesion, ie, the process by which cells attach to neighbouring cells and a supporting …