Abstract The Rho family of GTPases are highly conserved molecular switches that control
some of the most fundamental processes of cell biology, including morphogenesis, vesicular …

Background The small GTPase Rho1 has been shown to regulate the organization of the
actin cytoskeleton and formation of the cell wall in the fission yeast Schizosaccharomyces …

The Schizosaccharomyces pombe exchange factor Rgf1p specifically regulates Rho1p
during polarized growth. Rgf1p activates the β-glucan synthase (GS) complex containing the …

Rho G‐proteins are critical for polarized growth, yet little is known about the dynamics of
their activation during fungal filamentous growth. We first investigated the roles of Rho 1 and …

The role of small G‐proteins in PTH‐stimulated PKC translocation and IL‐6 promoter
expression in UMR‐106 cells was determined. The effects of PTH (1–34) and PTH (3–34) in …

Rho GTPase-activating proteins (GAPs) are responsible for the inactivation of Rho GTPases,
which are involved in the regulation of critical biological responses in eukaryotic cells …

The cell wall is important for maintenance of the structural integrity and morphology of fungal
cells. Besides β-glucan and chitin, α-glucan is a major polysaccharide in the cell wall of …

To investigate the contributions of phosphatidylserine to the growth and morphogenesis of
the rod-shaped fission yeast Schizosaccharomyces pombe, we have characterized the …

Rho GTPases, activated by guanine nucleotide exchange factors (GEFs), are essential
regulators of polarized cell growth, cytokinesis, and many other cellular processes …

The fission yeast protein kinase C (PKC) ortholog Pck2 controls cell wall synthesis and is a
major upstream activator of the cell integrity pathway (CIP) and its core component, the MAP …