Cell morphogenesis is a complex process that depends on cytoskeleton and membrane
organization, intracellular signalling and vesicular trafficking. The rod shape of the fission …

The cell-integrity and stress-response MAP kinase pathways (CIP and SRP, respectively)
are stimulated by various environmental stresses. Ssp1 kinase modulates actin dynamics …

Cell growth in S. pombe is a complex process necessarily related to cell wall biosynthesis
(Ishiguro 1998, for review). The cell wall is the rigid structure that provides mechanical …

The cps5-138 fission yeast mutant shows an abnormal lemon-like morphology at 28° C in
minimal medium and a lethal thermosensitive phenotype at 37° C. Cell growth is completely …

Rho1p is a membrane-associated protein that belongs to the Rho family of small GTPases.
These proteins coordinate processes such as actin remodelling and polarised secretion to …

In fission yeast, calcineurin is required for cytokinesis and ion homeostasis; however, most
of its physiological roles remain obscure. To identify genes that share an essential function …

Protein farnesyltransferase (FTase) plays important roles in the growth and differentiation of
eukaryotic cells. In this paper, we report the identification of theSchizosaccharomyces …

Pmk1, a fission yeast homologue of mammalian ERK MAPK, regulates cell wall integrity,
cytokinesis, RNA granule formation and ion homeostasis. Our screen for vic (viable in the …

Cytokinesis is a complicated yet conserved step of the cell-division cycle that requires the
coordination of multiple proteins and cellular processes. Here we describe a previously …

The two PKC orthologs Pck1 and Pck2 in the fission yeast Schizosaccharomyces pombe
operate in a redundant fashion to control essential functions, including morphogenesis and …