MicroRNA: trends in clinical trials of cancer diagnosis and therapy strategies

T Kim, CM Croce - Experimental & molecular medicine, 2023 - nature.com
As a type of short noncoding RNAs, microRNA (miRNA) undoubtedly plays a crucial role in
cancer development. Since the discovery of the identity and clinical functions of miRNAs …

Elucidating the distinct contributions of miR-122 in the HCV life cycle reveals insights into virion assembly

M Rheault, SE Cousineau, DR Fox… - Nucleic Acids …, 2023 - academic.oup.com
Efficient hepatitis C virus (HCV) RNA accumulation is dependent upon interactions with the
human liver-specific microRNA, miR-122. MiR-122 has at least three roles in the HCV life …

Extracellular vesicles from mouse trophoblast cells: Effects on neural progenitor cells and potential participants in the placenta–brain axis

JA Kinkade, AS Seetharam, S Sachdev… - Biology of …, 2024 - academic.oup.com
The fetal brain of the mouse is thought to be dependent upon the placenta as a source of
serotonin (5-hydroxytryptamine; 5-HT) and other factors. How factors reach the developing …

Developing microRNAs as engineering tools to modulate monoclonal antibody galactosylation

F Klingler, P Schlossbauer, L Naumann… - Biotechnology and …, 2024 - Wiley Online Library
N‐linked glycosylation is one of the most important post‐translational modifications of
monoclonal antibodies (mAbs) and is considered to be a critical quality attribute (CQA), as …

Protein Glycosylation Patterns Shaped By the IRE1‐XBP1s Arm of the Unfolded Protein Response

K Chen, MD Shoulders - Israel Journal of Chemistry, 2024 - Wiley Online Library
The unfolded protein response (UPR) is a sensing and signaling pathway that surveys the
endoplasmic reticulum (ER) for protein folding challenges and responds whenever issues …

The Non-Coding RNA Journal Club: Highlights on Recent Papers—12

PKT Shiu, M Ilieva, A Holm, S Uchida, JK DiStefano… - Non-coding RNA, 2023 - mdpi.com
We are delighted to share with you our twelfth Journal Club and highlight some of the most
interesting papers published recently. We hope to keep you up-to-date with non-coding RNA …

The forecasting power of the mucin-microbiome interplay in livestock respiratory diseases

N Mach - Veterinary Quarterly, 2024 - Taylor & Francis
Complex respiratory diseases are a significant challenge for the livestock industry
worldwide. These diseases considerably impact animal health and welfare and cause …

Regulation of miRNA-155-5p ameliorates NETosis in pulmonary fibrosis rat model via inhibiting its target cytokines IL-1β, TNF-α and TGF-β1

RM Adel, H Helal, MA Fouad… - International …, 2024 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is an age-related inflammatory disease with no cure up till
now. It is accompanied by neutrophils infiltration as the main responders to inflammation …

[HTML][HTML] MicroRNA-320a enhances LRWD1 expression through the AGO2/FXR1-dependent pathway to affect cell behaviors and the oxidative stress response in …

YH Lin, CH Su, HM Chen, MS Wu, HA Pan… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
Background: Testicular cancer is fairly rare but can affect fertility in adult males. Leucine-rich
repeats-and WD repeat domain-containing protein 1 (LRWD1) is a sperm-specific marker …

Downregulation of ST6GAL2 Correlates to Liver Inflammation and Predicts Adverse Prognosis in Hepatocellular Carcinoma

R Liu, X Yu, X Cao, X Wang, Y Liang, W Qi… - Journal of …, 2024 - Taylor & Francis
Purpose ST6 Beta-Galactoside Alpha-2, 6-Sialyltransferase 2 (ST6GAL2), a member of the
sialic acid transferase family, is differentially expressed in diverse cancers. However, it …