A guide to cell death pathways
J Yuan, D Ofengeim - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Regulated cell death mediated by dedicated molecular machines, known as programmed
cell death, plays important roles in health and disease. Apoptosis, necroptosis and …
cell death, plays important roles in health and disease. Apoptosis, necroptosis and …
Targeting ferroptosis opens new avenues for the development of novel therapeutics
S Sun, J Shen, J Jiang, F Wang, J Min - Signal transduction and …, 2023 - nature.com
Ferroptosis is an iron-dependent form of regulated cell death with distinct characteristics,
including altered iron homeostasis, reduced defense against oxidative stress, and abnormal …
including altered iron homeostasis, reduced defense against oxidative stress, and abnormal …
The cell biology of ferroptosis
SJ Dixon, JA Olzmann - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Ferroptosis is a non-apoptotic cell death mechanism characterized by iron-dependent
membrane lipid peroxidation. Here, we review what is known about the cellular mechanisms …
membrane lipid peroxidation. Here, we review what is known about the cellular mechanisms …
7-Dehydrocholesterol dictates ferroptosis sensitivity
Y Li, Q Ran, Q Duan, J Jin, Y Wang, L Yu, C Wang… - Nature, 2024 - nature.com
Ferroptosis, a form of regulated cell death that is driven by iron-dependent phospholipid
peroxidation, has been implicated in multiple diseases, including cancer,–, degenerative …
peroxidation, has been implicated in multiple diseases, including cancer,–, degenerative …
A guideline on the molecular ecosystem regulating ferroptosis
Ferroptosis, an intricately regulated form of cell death characterized by uncontrolled lipid
peroxidation, has garnered substantial interest since this term was first coined in 2012 …
peroxidation, has garnered substantial interest since this term was first coined in 2012 …
The diversified role of mitochondria in ferroptosis in cancer
Ferroptosis is a form of regulated cell death induced by iron-dependent lipid peroxidation,
and it has been studied extensively since its discovery in 2012. Induced by iron overload …
and it has been studied extensively since its discovery in 2012. Induced by iron overload …
A DNA tetrahedron-based ferroptosis-suppressing nanoparticle: superior delivery of curcumin and alleviation of diabetic osteoporosis
Y Li, Z Cai, W Ma, L Bai, E Luo, Y Lin - Bone Research, 2024 - nature.com
Diabetic osteoporosis (DOP) is a significant complication that poses continuous threat to the
bone health of patients with diabetes; however, currently, there are no effective treatment …
bone health of patients with diabetes; however, currently, there are no effective treatment …
The biochemical pathways of apoptotic, necroptotic, pyroptotic, and ferroptotic cell death
Apoptosis, the first regulated form of cell death discovered in mammalian cells, is executed
by caspase-3/7, which are dormant in living cells but become activated by upstream …
by caspase-3/7, which are dormant in living cells but become activated by upstream …
Targeting epigenetic and posttranslational modifications regulating ferroptosis for the treatment of diseases
Y Wang, J Hu, S Wu, JS Fleishman, Y Li, Y Xu… - … and Targeted Therapy, 2023 - nature.com
Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …
Lipid quality control and ferroptosis: from concept to mechanism
Cellular quality control systems sense and mediate homeostatic responses to prevent the
buildup of aberrant macromolecules, which arise from errors during biosynthesis, damage …
buildup of aberrant macromolecules, which arise from errors during biosynthesis, damage …