How cells move is a fundamental biological question. The directionality of adherent
migrating cells depends on the assembly and disassembly (turnover) of focal adhesions …

The cytoskeleton comprises three polymerizing structures that have been studied for a long
time, actin microfilaments, microtubules and intermediate filaments, plus more recently …

Septins are cytoskeletal proteins conserved from algae and protists to mammals. A unique
feature of septins is their presence as heteromeric complexes that polymerize into filaments …

Background Septins are cytoskeletal proteins with filament forming capabilities, which have
multiple roles during cell division, cellular polarization, morphogenesis, and membrane …

Long-range membrane traffic is guided by microtubule-associated proteins and
posttranslational modifications, which collectively comprise a traffic code. The regulatory …

Cleavage of one cell into two is the most dramatic event in the life of a cell. Plasma
membrane fission occurs within a narrow intercellular bridge (ICB) between the daughter …

The molecular basis for septin filament assembly has begun to emerge over recent years.
These filaments are essential for many septin functions which depend on their association …

Pyramidal neurons are a major cell type of the forebrain, consisting of a pyramidally shaped
soma with axonal and apicobasal dendritic processes. It is poorly understood how the …

Septins are highly conserved GTP‐binding proteins that oligomerize and form higher order
structures. The septin cytoskeleton plays an important role in cellular organization …

The microtubule cytoskeleton consists of microtubule subsets with distinct compositions of
microtubule-associated proteins, which instruct the position and traffic of subcellular …