This article reviews the past and current statuses of time-domain near-infrared spectroscopy
(TD-NIRS) and imaging. Although time-domain technology is not yet widely employed due to …

In the field of biomedical image reconstruction, functional near infra-red spectroscopy
(fNIRs) is a promising technology that uses near infra-red light for non-invasive imaging and …

Perturbation Monte Carlo (pMC) has been previously proposed to rapidly recompute optical
measurements when small perturbations of optical properties are considered, but it was …

Monte Carlo methods are commonly used as the gold standard in modeling photon transport
through turbid media. With the rapid development of structured light applications, an …

Time-resolved fluorescence optical tomography allows 3-dimensional localization of
multiple fluorophores based on lifetime contrast while providing a unique data set for …

The Monte Carlo Command Line application (MCCL) is an open-source software package
that provides Monte Carlo simulations of radiative transport through heterogeneous turbid …

Time domain fluorescence molecular tomography (TD-FMT) provides a unique dataset for
enhanced quantification and spatial resolution. The time-gate dataset can be divided into …

Purpose: The Monte Carlo method is an accurate model for time‐resolved quantitative
fluorescence tomography. However, this method suffers from low computational efficiency …

In this experimental investigation, we explore the feasibility of using wide-field illumination
for time-resolved fluorescence molecular tomography. The performance of wide-field …

The design and characterization of a time-resolved functional imager using a wide-field
excitation scheme for small animal imaging is described. The optimal operation parameters …