Colorectal cancer (CRC) is a substantial source of global morbidity and mortality in dire
need of improved prevention and treatment strategies. As our understanding of CRC grows …

Colorectal cancer (CRC) incidence rates decreased by up to 50% in older age groups in the
USA in the era of the widespread uptake of screening colonoscopy, despite adverse trends …

Systemic characterisation of the human faecal microbiome provides the opportunity to
develop non-invasive approaches in the diagnosis of a major human disease. However …

This article presents global cancer statistics by world region for the year 2022 based on
updated estimates from the International Agency for Research on Cancer (IARC). There …

Aim Long non-coding RNA (LncRNA) telomerase RNA component (TERC) has telomerase-
dependent and independent activity in numerous cancer types. The present study purposes …

Importance Noninvasive tests for colorectal cancer screening must include sensitive
detection of colorectal cancer and precancerous lesions. These tests must be validated for …

Colorectal cancer (CRC) is one of the most common malignancies that is usually detected
late in the clinic. The currently available diagnostic tools for CRC are either invasive or …

The epithelial–mesenchymal transition (EMT) is a cellular reprogramming process that
occurs during embryonic development and adult tissue homeostasis. This process involves …

Background Colorectal cancer (CRC) is often diagnosed in advanced stages. Circulating
tumour DNA (ctDNA) has been proposed as an early diagnostic biomarker. However, as a …

Simple Summary Almost all cell types produce extracellular vesicles that, according to their
size, subcellular origin and release pathways, are mainly categorized as exosomes …