Colorectal cancer (CRC) is a substantial source of global morbidity and mortality in dire
need of improved prevention and treatment strategies. As our understanding of CRC grows …

The epithelial–mesenchymal transition (EMT) is a cellular reprogramming process that
occurs during embryonic development and adult tissue homeostasis. This process involves …

Systemic characterisation of the human faecal microbiome provides the opportunity to
develop non-invasive approaches in the diagnosis of a major human disease. However …

Aim Long non-coding RNA (LncRNA) telomerase RNA component (TERC) has telomerase-
dependent and independent activity in numerous cancer types. The present study purposes …

Background Early detection and prognosis prediction of colorectal cancer (CRC) can
significantly reduce CRC-related mortality. Recently, circulating tumour DNA (ctDNA) …

The extensive morbidity of colorectal cancer (CRC) and the inferior prognosis of terminal
CRC urgently call for reliable prognostic biomarkers. For this, we identified 704 differentially …

Background Colorectal cancer (CRC) is often diagnosed in advanced stages. Circulating
tumour DNA (ctDNA) has been proposed as an early diagnostic biomarker. However, as a …

Background: MicroRNA (miRNA) has been linked to colorectal cancer (CRC) tumorigenesis
due to its post-transcriptional mechanism in targeting cancer-associated genes. Although …

Currently, women are disadvantaged compared to men in colorectal cancer (CRC)
screening, particularly in programmes that use faecal immunochemical tests for …

Purpose The credible data about the burden of early-onset colorectal cancer (EOCRC) in
China when compared to other countries in the group of twenty (G20) remained unavailable …