Regulatory circuitry governing fungal development, drug resistance, and disease
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …
frequency of fungal infections in immunocompromised populations and the limited …
Candida albicans: A molecular revolution built on lessons from budding yeast
J Berman, PE Sudbery - Nature Reviews Genetics, 2002 - nature.com
Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, in immunocompromised patients …
gastrointestinal flora of most healthy humans. However, in immunocompromised patients …
[HTML][HTML] Oxidative Stress Responses in the Human Fungal Pathogen, Candida albicans
Candida albicans is a major fungal pathogen of humans, causing approximately 400,000 life-
threatening systemic infections world-wide each year in severely immunocompromised …
threatening systemic infections world-wide each year in severely immunocompromised …
Morphogenesis in Candida albicans
M Whiteway, C Bachewich - Annu. Rev. Microbiol., 2007 - annualreviews.org
Candida albicans is termed a dimorphic fungus because it proliferates in either a yeast form
or a hyphal form. The switch between these forms is the result of a complex interplay of …
or a hyphal form. The switch between these forms is the result of a complex interplay of …
[HTML][HTML] Genome-wide fitness test and mechanism-of-action studies of inhibitory compounds in Candida albicans
D Xu, B Jiang, T Ketela, S Lemieux, K Veillette… - PLoS …, 2007 - journals.plos.org
Candida albicans is a prevalent fungal pathogen amongst the immunocompromised
population, causing both superficial and life-threatening infections. Since C. albicans is …
population, causing both superficial and life-threatening infections. Since C. albicans is …
Hgc1, a novel hypha‐specific G1 cyclin‐related protein regulates Candida albicans hyphal morphogenesis
The human fungal pathogen Candida albicans switches from yeast to hyphal growth when
exposed to serum or phagocytosed. However, the importance of this morphological switch …
exposed to serum or phagocytosed. However, the importance of this morphological switch …
Morphogenesis and cell cycle progression in Candida albicans
J Berman - Current opinion in microbiology, 2006 - Elsevier
Candida albicans, an opportunistic human pathogen, displays three modes of growth: yeast,
pseudohyphae and true hyphae, all of which differ both in morphology and in aspects of cell …
pseudohyphae and true hyphae, all of which differ both in morphology and in aspects of cell …
Ectopic expression of URA3 can influence the virulence phenotypes and proteome of Candida albicans but can be overcome by targeted reintegration of URA3 at the …
Uridine auxotrophy, based on disruption of both URA3 alleles in diploid Candida albicans
strain SC5314, has been widely used to select gene deletion mutants created in this fungus …
strain SC5314, has been widely used to select gene deletion mutants created in this fungus …
Candida morphogenesis and host–pathogen interactions
M Whiteway, U Oberholzer - Current opinion in microbiology, 2004 - Elsevier
The human fungal pathogen Candida albicans has many morphological forms. Recent
advances in genomics and cell biology are providing an improved understanding of the …
advances in genomics and cell biology are providing an improved understanding of the …
Modulation of morphogenesis in Candida albicans by various small molecules
J Shareck, P Belhumeur - Eukaryotic cell, 2011 - Am Soc Microbiol
The pathogenic yeast Candida albicans, a member of the mucosal microbiota, is
responsible for a large spectrum of infections, ranging from benign thrush and vulvovaginitis …
responsible for a large spectrum of infections, ranging from benign thrush and vulvovaginitis …