Purpose This review provides an update on the current clinical, epidemiological and
pathophysiological evidence alongside the diagnostic, prevention and treatment approach …

Peripheral neuropathies are characterized by nerves damage and axonal loss, and they
could be classified in hereditary or acquired forms. Acquired peripheral neuropathies are …

Vincristine-induced peripheral neurotoxicity (VIPN) is a very common side effect of
vincristine chemotherapy among pediatric patients with cancer. Neuropathy may be sensory …

Vincristine, a chemotherapeutic microtubule formation inhibitor, is used to treat all stages of
prostate cancer. To enhance drug delivery at the specific site and increase the efficiency of …

Simple Summary The survival rate for pediatric cancers has improved significantly over the
last decades. Conventional chemotherapies play a vital role in pediatric cancer treatment …

Diffuse large B-cell lymphoma (DLBCL) is an aggressive but potentially curable disease and
is most common in older people. Rituximab-CHOP (cyclophosphamide, doxorubicin …

Background The anticancer drug vincristine is associated with potentially dose-limiting side-
effects, including neurotoxicity and myelosuppression. However, there currently exists a lack …

Vincristine (VCR) is a well-known chemotherapeutic agent that frequently triggers
neuropathic pain. Ajugarin-I (Aju-I) isolated from Ajuga bracteosa exerts antioxidant, anti …

The administration of antifungals for therapeutic and, especially, prophylactic purposes is
virtually a constant in patients requiring hematology-oncology treatment. Any attempt to …

Simple Summary Alkaloids are natural products that possess numerous pharmacological
activities and have been exploited effectively to treat cancer. However, the clinically …