In the present work, we report compilation and analysis of 245 drugs, including small and
macromolecules approved by the US FDA from 2015 until June 2020. Nearly 29% of the …

The lungs are constantly exposed to inhaled debris, allergens, pollutants, commensal or
pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …

Background A novel coronavirus (CoV), severe acute respiratory syndrome (SARS)–CoV-2,
has infected> 75 000 individuals and spread to> 20 countries. It is still unclear how fast the …

COVID-19 remains a serious emerging global health problem, and little is known about the
role of oropharynx commensal microbes in infection susceptibility and severity. Here, we …

SARS-CoV-2 infection causes COVID-19 disease, which can result in consequences
ranging from undetectable to fatal, focusing attention on the modulators of outcomes. The …

Bacterial-viral interactions in saliva have been associated with morbidity and mortality for
respiratory viruses such as influenza and SARS-CoV. However, such transkingdom …

Infection with influenza can be aggravated by bacterial co-infections, which often results in
disease exacerbation. The effects of influenza infection on the upper respiratory tract (URT) …

Viral infections are influenced by various microorganisms in the environment surrounding
the target tissue, and the correlation between the type and balance of commensal microbiota …

Background Prophylactic strategies are urgently needed for prevention of severe
inflammatory responses to respiratory viral infections. Bacterial-host interactions may modify …

Respiratory tract microbiome is closely related to respiratory tract infections, while
characterization of oropharyngeal microbiome in recovered coronavirus disease 2019 …