Microglial Dynamics Modulate Vestibular Compensation in a Rodent Model of Vestibulopathy and Condition the Expression of Plasticity Mechanisms in the …
N El Mahmoudi, E Marouane, G Rastoldo, D Pericat… - Cells, 2022 - mdpi.com
Unilateral vestibular loss (UVL) induces a vestibular syndrome composed of posturo-
locomotor, oculomotor, vegetative, and perceptivo-cognitive symptoms. With time, these …
locomotor, oculomotor, vegetative, and perceptivo-cognitive symptoms. With time, these …
The role of microglia in chronic pain and depression: innocent bystander or culprit?
N Yin, E Yan, W Duan, C Mao, Q Fei, C Yang, Y Hu… - …, 2021 - Springer
Clinical evidence shows that chronic pain and depression often accompany each other, but
the underlying pathogenesis of comorbid chronic pain and depression remains mostly …
the underlying pathogenesis of comorbid chronic pain and depression remains mostly …
Pain, depression and inflammation: are interconnected causative factors involved?
BE Leonard - Pain in psychiatric disorders, 2015 - karger.com
Co-morbid depression and chronic pain are highly prevalent. The purpose of this review is
to examine the role of chronic inflammation as a common mediator of these co-morbidities …
to examine the role of chronic inflammation as a common mediator of these co-morbidities …
Acanthoscurria gomesiana spider‐derived Mygalin in the prelimbic prefrontal cortex modulates neuropathic pain and depression comorbid
AC Medeiros, P Medeiros, RN Ruggiero… - … of Biochemical and …, 2023 - Wiley Online Library
Depression has a high rate of comorbidity with neuropathic pain. This study aims to
investigate the effect of Mygalin, an acylpolyamine synthesized from a natural molecule in …
investigate the effect of Mygalin, an acylpolyamine synthesized from a natural molecule in …
IRF5 signaling in phagocytes is detrimental to neonatal hypoxic ischemic encephalopathy
A Al Mamun, H Yu, R Sharmeen… - Translational stroke …, 2021 - Springer
Immune responses to neonatal hypoxic ischemic encephalopathy (HIE) exacerbate brain
injury. Phagocytes, including microglia, play a central role in the immune response, but how …
injury. Phagocytes, including microglia, play a central role in the immune response, but how …
The anxiolytic drug buspirone prevents rotenone-induced toxicity in a mouse model of Parkinson's disease
S Thomas Broome, A Castorina - International Journal of Molecular …, 2022 - mdpi.com
A pharmacological and genetic blockade of the dopamine D3 receptor (D3R) has shown to
be neuroprotective in models of Parkinson's disease (PD). The anxiolytic drug buspirone, a …
be neuroprotective in models of Parkinson's disease (PD). The anxiolytic drug buspirone, a …
Mediterranean diet protects against a neuroinflammatory cortical transcriptome: Associations with brain volumetrics, peripheral inflammation, social isolation, and …
Mediterranean diets may be neuroprotective and prevent cognitive decline relative to
Western diets; however, the underlying biology is poorly understood. We assessed the …
Western diets; however, the underlying biology is poorly understood. We assessed the …
Minocycline reduces mechanical allodynia and depressive-like behaviour in type-1 diabetes mellitus in the rat
D Amorim, S Puga, R Braganca, A Braga… - Behavioural brain …, 2017 - Elsevier
A common and devastating complication of diabetes mellitus is painful diabetic neuropathy
(PDN) that can be accompanied by emotional disorders such as depression. A few studies …
(PDN) that can be accompanied by emotional disorders such as depression. A few studies …
[HTML][HTML] Inflammation increases the development of depression behaviors in male rats after spinal cord injury
Abstract Following spinal cord injury, 18–26% of patients are diagnosed with depressive
disorders, compared to 8–12% in the general population. As increased inflammation …
disorders, compared to 8–12% in the general population. As increased inflammation …
Repeated forced swim stress differentially affects formalin-evoked nociceptive behaviour and the endocannabinoid system in stress normo-responsive and stress …
EM Jennings, BN Okine, WM Olango, M Roche… - Progress in Neuro …, 2016 - Elsevier
Repeated exposure to a homotypic stressor such as forced swimming enhances nociceptive
responding in rats. However, the influence of genetic background on this stress-induced …
responding in rats. However, the influence of genetic background on this stress-induced …