Cellular switching from an epithelial-to-mesenchymal phenotype, and conversely from a
mesenchymal-toepithelial phenotype, are important biological programs that are operative …

Cardiogenesis is an exquisitely sensitive process. Any perturbation in the cells that
contribute to the building of the heart leads to cardiac malformations, which frequently result …

Stem-cell differentiation to desired lineages requires navigating alternating developmental
paths that often lead to unwanted cell types. Hence, comprehensive developmental …

The lateral plate mesoderm (LPM) forms the progenitor cells that constitute the heart and
cardiovascular system, blood, kidneys, smooth muscle lineage and limb skeleton in the …

Cranial placodes are specialized regions of the ectoderm, which give rise to various sensory
ganglia and contribute to the pituitary gland and sensory organs of the vertebrate head …

When and how cells form and pattern the myocardium is a central issue for heart
morphogenesis. Many genes are differentially expressed and function in subsets of …

Our goal here is to set out the types of unitary decisions made by heart progenitor cells, from
their appearance in the heart field until they form the simple heart tube. This provides a …

The sensory nervous system in the vertebrate head arises from two different cell
populations: neural crest and placodal cells. By contrast, in the trunk it originates from neural …

We have used carbocyanine dyes to fate map the primitive streak in the early chick embryo,
from stages 3+(mid-primitive streak) to 9 (8 somites). We show that presumptive notochord …

The secondary heart field is a conserved developmental domain in avian and mammalian
embryos that contributes myocardium and smooth muscle to the definitive cardiac arterial …