The therapeutic potential of purified cannabidiol

SE O'Sullivan, SS Jensen, GN Nikolajsen… - Journal of Cannabis …, 2023 - Springer
The use of cannabidiol (CBD) for therapeutic purposes is receiving considerable attention,
with speculation that CBD can be useful in a wide range of conditions. Only one product, a …

Phytocannabinoids in the pharmacotherapy of psoriasis

A Wroński, I Jarocka-Karpowicz, A Stasiewicz… - Molecules, 2023 - mdpi.com
Phytocannabinoids are naturally occurring compounds, the main source of which is
Cannabis sativa L. Through direct action or interaction with G protein-coupled receptors …

[HTML][HTML] The role of cannabidiol in aging

B Ni, Y Liu, M Dai, J Zhao, Y Liang, X Yang… - Biomedicine & …, 2023 - Elsevier
Aging is usually considered a key risk factor associated with multiple diseases, such as
neurodegenerative diseases, cardiovascular diseases and cancer. Furthermore, the burden …

Strategies to improve cannabidiol bioavailability and drug delivery

SE O'Sullivan, SS Jensen, AR Kolli, GN Nikolajsen… - Pharmaceuticals, 2024 - mdpi.com
The poor physicochemical properties of cannabidiol (CBD) hamper its clinical development.
The aim of this review was to examine the literature to identify novel oral products and …

Cannabinoids and endocannabinoids as therapeutics for nervous system disorders: preclinical models and clinical studies

RS Duncan, SM Riordan, MC Gernon… - Neural Regeneration …, 2024 - journals.lww.com
Cannabinoids are lipophilic substances derived from Cannabis sativa that can exert a
variety of effects in the human body. They have been studied in cellular and animal models …

Cannabidiol (CBD) products for pain: ineffective, expensive, and with potential harms

A Moore, S Straube, E Fisher, C Eccleston - The Journal of Pain, 2024 - Elsevier
Cannabidiol (CBD) attracts considerable attention for promoting good health and treating
various conditions, predominantly pain, often in breach of advertising rules. Examination of …

[HTML][HTML] Update on cannabidiol clinical toxicity and adverse effects: a systematic review

G Madeo, A Kapoor, R Giorgetti… - Current …, 2023 - ncbi.nlm.nih.gov
Background Compelling evidence from preclinical and clinical studies supports the
therapeutic role of cannabidiol (CBD) in several medical disorders. We reviewed the …

Topical cannabidiol is well tolerated in individuals with a history of elite physical performance and chronic lower extremity pain

N Hall, B James, MAN Bhuiyan, E Crane… - Journal of Cannabis …, 2023 - Springer
Introduction Cannabidiol (CBD) is a potential therapeutic for pain management. Yet, there
exists a dearth of studies of its tolerability and efficacy, especially in special populations …

The dual role of cannabidiol on monocyte-derived dendritic cell differentiation and maturation

Z Pénzes, S Alimohammadi, D Horváth, A Oláh… - Frontiers in …, 2023 - frontiersin.org
Introduction Extracts and compounds isolated from hemp (Cannabis sativa) are increasingly
gaining popularity in the treatment of a number of diseases, with topical formulations for …

[HTML][HTML] Cannabidiol and Intestinal Motility: A Systematic Review

G Story, CE Briere, DJ McClements, DA Sela - Current Developments in …, 2023 - Elsevier
Cannabidiol (CBD) is a non-intoxicating cannabinoid extracted from the cannabis plant that
is used for medicinal purposes. Ingestion of CBD is claimed to address several pathologies …