Aneuploidy in mammalian oocytes and the impact of maternal ageing

C Charalambous, A Webster, M Schuh - Nature Reviews Molecular Cell …, 2023 - nature.com
During fertilization, the egg and the sperm are supposed to contribute precisely one copy of
each chromosome to the embryo. However, human eggs frequently contain an incorrect …

Particulate matter air pollutants and cardiovascular disease: Strategies for intervention

A Aryal, AC Harmon, TR Dugas - Pharmacology & therapeutics, 2021 - Elsevier
Air pollution is consistently linked with elevations in cardiovascular disease (CVD) and CVD-
related mortality. Particulate matter (PM) is a critical factor in air pollution-associated CVD …

[图书][B] Genomes 5

TA Brown - 2023 - taylorfrancis.com
Genomes 5 has been completely revised and updated. It is a thoroughly modern textbook
about genomes and how they are investigated. As with previous Genomes editions …

Determining a multimodal aging clock in a cohort of Chinese women

J Li, M Xiong, XH Fu, Y Fan, C Dong, X Sun, F Zheng… - Med, 2023 - cell.com
Background Translating aging rejuvenation strategies into clinical practice has the potential
to address the unmet needs of the global aging population. However, to successfully do so …

Alcohol consumption and telomere length: Mendelian randomization clarifies alcohol's effects

A Topiwala, B Taschler, KP Ebmeier, S Smith… - Molecular …, 2022 - nature.com
Alcohol's impact on telomere length, a proposed marker of biological aging, is unclear. We
performed the largest observational study to date (in n= 245,354 UK Biobank participants) …

Inverted U-shaped relationship between sleep duration and phenotypic age in US adults: a population-based study

Y You, Y Chen, R Liu, Y Zhang, M Wang, Z Yang… - Scientific Reports, 2024 - nature.com
Sleep is a modifiable behavior that can be targeted in interventions aimed at promoting
healthy aging. This study aims to (i) identify the sleep duration trend in US adults;(ii) …

[HTML][HTML] Ranking biomarkers of aging by citation profiling and effort scoring

A Hartmann, C Hartmann, R Secci, A Hermann… - Frontiers in …, 2021 - frontiersin.org
Aging affects most living organisms and includes the processes that reduce health and
survival. The chronological and the biological age of individuals can differ remarkably, and …

How to slow down the ticking clock: age-associated epigenetic alterations and related interventions to extend life span

AM Galow, S Peleg - Cells, 2022 - mdpi.com
Epigenetic alterations pose one major hallmark of organismal aging. Here, we provide an
overview on recent findings describing the epigenetic changes that arise during aging and …

Telomeres and mitochondrial metabolism: implications for cellular senescence and age-related diseases

X Gao, X Yu, C Zhang, Y Wang, Y Sun, H Sun… - Stem cell reviews and …, 2022 - Springer
Cellular senescence is an irreversible cell arrest process, which is determined by a variety of
complicated mechanisms, including telomere attrition, mitochondrial dysfunction, metabolic …

Retinal age gap as a predictive biomarker of future risk of Parkinson's disease

W Hu, W Wang, Y Wang, Y Chen, X Shang… - Age and …, 2022 - academic.oup.com
Introduction retinal age derived from fundus images using deep learning has been verified
as a novel biomarker of ageing. We aim to investigate the association between retinal age …