Aneuploidy in mammalian oocytes and the impact of maternal ageing
C Charalambous, A Webster, M Schuh - Nature Reviews Molecular Cell …, 2023 - nature.com
During fertilization, the egg and the sperm are supposed to contribute precisely one copy of
each chromosome to the embryo. However, human eggs frequently contain an incorrect …
each chromosome to the embryo. However, human eggs frequently contain an incorrect …
Particulate matter air pollutants and cardiovascular disease: Strategies for intervention
Air pollution is consistently linked with elevations in cardiovascular disease (CVD) and CVD-
related mortality. Particulate matter (PM) is a critical factor in air pollution-associated CVD …
related mortality. Particulate matter (PM) is a critical factor in air pollution-associated CVD …
Determining a multimodal aging clock in a cohort of Chinese women
Background Translating aging rejuvenation strategies into clinical practice has the potential
to address the unmet needs of the global aging population. However, to successfully do so …
to address the unmet needs of the global aging population. However, to successfully do so …
Alcohol consumption and telomere length: Mendelian randomization clarifies alcohol's effects
Alcohol's impact on telomere length, a proposed marker of biological aging, is unclear. We
performed the largest observational study to date (in n= 245,354 UK Biobank participants) …
performed the largest observational study to date (in n= 245,354 UK Biobank participants) …
Inverted U-shaped relationship between sleep duration and phenotypic age in US adults: a population-based study
Y You, Y Chen, R Liu, Y Zhang, M Wang, Z Yang… - Scientific Reports, 2024 - nature.com
Sleep is a modifiable behavior that can be targeted in interventions aimed at promoting
healthy aging. This study aims to (i) identify the sleep duration trend in US adults;(ii) …
healthy aging. This study aims to (i) identify the sleep duration trend in US adults;(ii) …
[HTML][HTML] Ranking biomarkers of aging by citation profiling and effort scoring
A Hartmann, C Hartmann, R Secci, A Hermann… - Frontiers in …, 2021 - frontiersin.org
Aging affects most living organisms and includes the processes that reduce health and
survival. The chronological and the biological age of individuals can differ remarkably, and …
survival. The chronological and the biological age of individuals can differ remarkably, and …
How to slow down the ticking clock: age-associated epigenetic alterations and related interventions to extend life span
Epigenetic alterations pose one major hallmark of organismal aging. Here, we provide an
overview on recent findings describing the epigenetic changes that arise during aging and …
overview on recent findings describing the epigenetic changes that arise during aging and …
Telomeres and mitochondrial metabolism: implications for cellular senescence and age-related diseases
X Gao, X Yu, C Zhang, Y Wang, Y Sun, H Sun… - Stem cell reviews and …, 2022 - Springer
Cellular senescence is an irreversible cell arrest process, which is determined by a variety of
complicated mechanisms, including telomere attrition, mitochondrial dysfunction, metabolic …
complicated mechanisms, including telomere attrition, mitochondrial dysfunction, metabolic …
Retinal age gap as a predictive biomarker of future risk of Parkinson's disease
Introduction retinal age derived from fundus images using deep learning has been verified
as a novel biomarker of ageing. We aim to investigate the association between retinal age …
as a novel biomarker of ageing. We aim to investigate the association between retinal age …