Effect of air pollution on asthma

X Zhou, V Sampath, KC Nadeau - Annals of Allergy, Asthma & Immunology, 2024 - Elsevier
Asthma is a chronic inflammatory airway disease characterized by respiratory symptoms,
variable airflow obstruction, bronchial hyperresponsiveness, and airway inflammation …

Targeted therapeutics delivery by exploiting biophysical properties of senescent cells

J Low, B Chan, A Tay - Advanced Functional Materials, 2022 - Wiley Online Library
Cellular senescence refers to a state of irreversible arrest of cell proliferation in response to
various forms of cellular stress. It is known that the accumulation of senescent cells is a …

[HTML][HTML] Breaking down causes, consequences, and mediating effects of telomere length variation on human health

S Moix, MC Sadler, Z Kutalik, C Auwerx - Genome Biology, 2024 - Springer
Background Telomeres form repeated DNA sequences at the ends of chromosomes, which
shorten with each cell division. Yet, factors modulating telomere attrition and the health …

[HTML][HTML] Lipoprotein particle profiles associated with telomere length and telomerase complex components

N Novau-Ferré, M Rojas, L Gutierrez-Tordera, P Arcelin… - Nutrients, 2023 - mdpi.com
Telomere length (TL) is a well-known marker of age-related diseases. Oxidative stress and
inflammation increase the rate of telomere shortening, triggering cellular senescence …

Brain white matter hyperintensities-predicted age reflects neurovascular health in middle-to-old aged subjects

CC Huang, KH Chou, WJ Lee, AC Yang… - Age and …, 2022 - academic.oup.com
Background age-related neurovascular structural and functional impairment is a major
aetiology of dementia and stroke in older people. There is no single marker representative of …

[HTML][HTML] An update on healthspan and lifespan enhancing attributes of tea amidst the emerging understanding of aging biology

R Sharma, B Diwan - Human Nutrition & Metabolism, 2022 - Elsevier
A cellular senescence-centric understanding of biological aging and age-related chronic
diseases is rapidly emerging. As a result, strategies aimed at mitigating the deleterious …

Clinical and laboratory results in vaginal wall restoration using a fractional-pixel-CO2 laser: histological findings and changes in the Ki67 protein and telomere length

V Benitez-Roig, PA Martínez-Carpio, MA Trelles… - Lasers in Medical …, 2023 - Springer
Thermal deposition of laser energy in the vaginal epithelium in genitourinary syndrome of
menopause (GSM) results in clinical and biological effects, but many cellular and molecular …

Annual space weather fluctuations and telomere length dynamics in a longitudinal cohort of older men: the Normative Aging Study

T Zhai, CL Zilli Vieira, P Vokonas… - Journal of Exposure …, 2023 - nature.com
Background Space weather has been associated with increased risk of cardiovascular
diseases in space and flight crew. However, limited research has focused on the ground …

Socioeconomic-Status-Based Disrespect, Discrimination, Exclusion, and Shaming: A Potential Source of Health Inequalities?

BG Link, SJ García, R Firat… - Journal of Health …, 2024 - journals.sagepub.com
Observing an association between socioeconomic status (SES) and health reliably leads to
the question,“What are the pathways involved?” Despite enormous investment in research …

[HTML][HTML] Telomere maintenance in African trypanosomes

B Li - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
Telomere maintenance is essential for genome integrity and chromosome stability in
eukaryotic cells harboring linear chromosomes, as telomere forms a specialized structure to …