A mis padres, por auparme en los momentos buenos y levantarme en los malos, por
trasmitirme, sin yo darme cuenta, todas las virtudes que los demás ven en mí, por ser en …

Chronic myeloid leukemia (CML) represents about 15% of all leukemia cases. Although the
incidence of the disease is rather low, the therapeutic progress of the last decade has …

Exosomes, biologically active extracellular vesicles, are derived from normal and neoplastic
cells. Emerging evidence revealed that exosomes modulate cell-cell communication and …

Background BCR-ABL kinase domain (KD) mutations are detected in approximately 45% of
imatinib-resistant CML. Patterns of KD mutations in Philadelphia chromosome (Ph)+ acute …

The clinical outcomes and survival of tyrosine kinase inhibitor (TKI)-treated patients with
chronic myeloid leukemia (CML) have been significantly improved. The aim of this editorial …

This review highlights major achievements of the Russian oncology in the past decades,
such as works of NN Petrov, LA Zilber, NN Blokhin, EE Pogosyants. Revolutionary shift in …

O imatinibe tem sido confirmado como terapia de primeira linha para a Leucemia Mielóide
Crônica (LMC) por apresentar respostas duradouras na maior parte dos pacientes …

Chronic myeloid leukemia (CML) is characterized by reciprocal translocation between
chromosome 9 and 22. This translocation will activate the tyrosin kinase, leads to underlying …

Lung cancer is the global leader in cancer related deaths, but treatment outcomes have
improved in recent years with the utilization of oncogene-targeted therapies. Here, we were …

Актуальность работы. В современном лечении раковых заболеваний крови и кожи
важное место занимает химиотерапия, обеспечивающая подавление роста …