The brain is supplied by an elaborate vascular network that originates extracranially and
reaches deep into the brain. The concept of the neurovascular unit provides a useful …

Post-cardiac arrest brain injury (PCABI) is caused by initial ischaemia and subsequent
reperfusion of the brain following resuscitation. In those who are admitted to intensive care …

Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …

A rise in body core temperature and loss of body water via sweating are natural
consequences of prolonged exercise in the heat. This review provides a comprehensive and …

Sedentary behaviour—put simply, too much sitting, as a distinct concept from too little
exercise—is a novel determinant of cardiovascular risk. This definition provides a …

Adults with type 2 diabetes are at an increased risk of developing certain brain or mental
disorders, including stroke, dementia, and depression. Although these disorders are not …

High-speed high-resolution imaging of the whole-brain hemodynamics is critically important
to facilitating neurovascular research. High imaging speed and image quality are crucial to …

Abstract In 1959, Niels Lassen illustrated the cerebral autoregulation curve in the classic
review article entitled Cerebral Blood Flow and Oxygen Consumption in Man. This concept …

We highlight a significant problem that needs to be considered and addressed when
performing functional near-infrared spectroscopy (fNIRS) studies, namely the possibility of …

Administration of anesthetic agents fundamentally shifts the responsibility for maintenance of
homeostasis from the patient and their intrinsic physiological regulatory mechanisms to the …