[HTML][HTML] Organ-on-a-chip meets artificial intelligence in drug evaluation

S Deng, C Li, J Cao, Z Cui, J Du, Z Fu, H Yang… - Theranostics, 2023 - ncbi.nlm.nih.gov
Drug evaluation has always been an important area of research in the pharmaceutical
industry. However, animal welfare protection and other shortcomings of traditional drug …

Global Literature Analysis of Organoid and Organ‐on‐Chip Research

J Shoji, RP Davis, CL Mummery… - Advanced healthcare …, 2023 - Wiley Online Library
Organoids and cells in organ‐on‐chip platforms replicate higher‐level anatomical,
physiological, or pathological states of tissues and organs. These technologies are widely …

Tris (2-chloroethyl) phosphate exerts hepatotoxic impacts on zebrafish by disrupting hypothalamic–pituitary–thyroid and gut–liver axes

D Tian, Y Yu, Y Yu, L Lu, D Tong, W Zhang… - Environmental …, 2023 - ACS Publications
The ubiquitous environmental presence of tris (2-chloroethyl) phosphate (TCEP) poses a
potential threat to animals; however, little is known about its hepatotoxicity. In this study, the …

The hepatotoxicity assessment of micro/nanoplastics: A preliminary study to apply the adverse outcome pathways

Y Ge, S Yang, T Zhang, X Wan, Y Zhu, F Yang… - Science of The Total …, 2023 - Elsevier
Plastic pollution has become a significant global problem over the years, leading to the
continuous decomposition and accumulation of micro/nanoplastics (MNPLs) in the …

Hepatotoxicity due to herbal dietary supplements: Past, present and the future

BJ Gurley, MR McGill, I Koturbash - Food and Chemical Toxicology, 2022 - Elsevier
Dietary supplements (DS) constitute a widely used group of products comprising vitamin,
mineral, and botanical extract formulations. DS of botanical or herbal origins (HDS) …

[HTML][HTML] Advances in microfluidics for single red blood cell analysis

GV Grigorev, AV Lebedev, X Wang, X Qian… - Biosensors, 2023 - mdpi.com
The utilizations of microfluidic chips for single RBC (red blood cell) studies have attracted
great interests in recent years to filter, trap, analyze, and release single erythrocytes for …

Dual mechanism (sunlight/dark) of the self-assembly nitazoxanide drug on cellulose nanocrystal surface for destroying the Cryptosporidium parvum oocysts

SR Khaleil, NM Mira, NF Ghanem… - International Journal of …, 2023 - Elsevier
Destruction of the cryptosporidium parvum (C. parvum) Oocysts is the main target of the work
via the improvement effect of the nitazoxanide (NTZ) drug by increasing the drug adsorption …

The Material World of 3D‐Bioprinted and Microfluidic‐Chip Models of Human Liver Fibrosis

AM Carvalho, R Bansal, CC Barrias… - Advanced …, 2024 - Wiley Online Library
Biomaterials are extensively used to mimic cell–matrix interactions, which are essential for
cell growth, function, and differentiation. This is particularly relevant when developing in vitro …

Integrating spheroid‐on‐a‐chip with tubeless rocker platform: A high‐throughput biological screening platform

S Kheiri, Z Chen, I Yakavets, F Rakhshani… - Biotechnology …, 2023 - Wiley Online Library
Spheroid‐on‐a‐chip platforms are emerging as promising in vitro models that enable
screening of the efficacy of biologically active ingredients. Generally, the supply of liquids to …

State-of-the-art advancements in liver-on-a-chip (LOC): integrated biosensors for LOC

M Liu, Y Xiang, Y Yang, X Long, Z Xiao, Y Nan… - Biosensors and …, 2022 - Elsevier
Liver models are vital for the liver diseases and drug research as many novel drugs.
However, traditional liver models cannot meet this need, mainly because they cannot …