Biological nanopore approach for singlemolecule protein sequencing

ZL Hu, MZ Huo, YL Ying, YT Long - Angewandte Chemie, 2021 - Wiley Online Library
Proteins are responsible for the occurrence and treatment of many diseases, and therefore
protein sequencing will revolutionize proteomics and clinical diagnostics. Biological …

Nanopore sensing

W Shi, AK Friedman, LA Baker - Analytical chemistry, 2017 - ACS Publications
Scope of the Review. Herein, we provide an up-to-date overview of the field of nanopore
sensing with emphases placed on the advances made in the most recent two years (2014 …

Overview of the materials design and sensing strategies of nanopore devices

L Liang, F Qin, S Wang, J Wu, R Li, Z Wang… - Coordination Chemistry …, 2023 - Elsevier
Nanopore platform holds a great fascination that attracts increasing interests in research and
leads the development of various domains. Herein we first briefly introduce the …

Biological nanopores: confined spaces for electrochemical single-molecule analysis

C Cao, YT Long - Accounts of chemical research, 2018 - ACS Publications
Conspectus Nanopore sensing is developing into a powerful single-molecule approach to
investigate the features of biomolecules that are not accessible by studying ensemble …

Identification of Conformational Variants for Bradykinin Biomarker Peptides from a Biofluid Using a Nanopore and Machine Learning

SJ Greive, L Bacri, B Cressiot, J Pelta - ACS nano, 2023 - ACS Publications
There is a current need to develop methods for the sensitive detection of peptide biomarkers
in complex mixtures of molecules, such as biofluids, to enable early disease detection …

Artificial cell membrane systems for biosensing applications

T Osaki, S Takeuchi - Analytical chemistry, 2017 - ACS Publications
Biological membranes provide a physical boundary that separates the inside and outside of
a cell or organelle. They also mediate signal transduction and transport of various molecules …

High-resolution size-discrimination of single nonionic synthetic polymers with a highly charged biological nanopore

G Baaken, I Halimeh, L Bacri, J Pelta, A Oukhaled… - Acs Nano, 2015 - ACS Publications
Electrophysiological studies of the interaction of polymers with pores formed by bacterial
toxins (1) provide a window on single molecule interaction with proteins in real time,(2) …

Single molecule nanopore spectrometry for peptide detection

AE Chavis, KT Brady, GA Hatmaker, CE Angevine… - ACS …, 2017 - ACS Publications
Sensing and characterization of water-soluble peptides is of critical importance in a wide
variety of bioapplications. Single molecule nanopore spectrometry (SMNS) is based on the …

The utility of nanopore technology for protein and peptide sensing

JWF Robertson, JE Reiner - Proteomics, 2018 - Wiley Online Library
Resistive pulse nanopore sensing enables labelfree singlemolecule analysis of a wide
range of analytes. An increasing number of studies have demonstrated the feasibility and …

Membrane protein-based biosensors

N Misawa, T Osaki, S Takeuchi - Journal of the Royal …, 2018 - royalsocietypublishing.org
This review highlights recent development of biosensors that use the functions of membrane
proteins. Membrane proteins are essential components of biological membranes and have a …