Candida parapsilosis is one of the most commen causes of life-threatening candidaemia,
particularly in premature neonates, individuals with cancer of the haematopoietic system …

Human fungal infections are a historically neglected area of disease research, yet they
cause more than 1.5 million deaths every year. Our understanding of the pathophysiology of …

While the fungus Candida albicans is a common colonizer of healthy humans, it is also
responsible for mucosal infections and severe invasive disease. Understanding the …

Candida species are a major cause of invasive fungal infections. While Candida albicans, C.
glabrata, C. parapsilosis, and C. tropicalis are the most dominant species causing life …

Candida species are the most prevalent cause of invasive fungal infections, of which
Candida albicans is the most common. Translocation across the epithelial barrier into the …

Successful pathogens require metabolic flexibility to adapt to diverse host niches. The
presence of co-infecting or commensal microorganisms at a given infection site can further …

For the human fungal pathogen Candida albicans, metabolic flexibility and the ability to
transition between yeast and filamentous growth states are key virulence traits that enable …

As part of the human microbiota, the fungus Candida albicans colonizes the oral cavity and
other mucosal surfaces of the human body. Commensalism is tightly controlled by complex …

Aneuploidy is a frequent occurrence in fungal species where it can alter gene expression
and promote adaptation to a variety of environmental cues. Multiple forms of aneuploidy …

Candida albicans is a commensal organism of the human gastrointestinal tract and a
prevalent opportunistic pathogen. It exhibits different morphogenic forms to survive in …