Recent advances in exosome-mediated nucleic acid delivery for cancer therapy
Y Zhang, Q Liu, X Zhang, H Huang, S Tang… - Journal of …, 2022 - Springer
Cancer is a leading public health problem worldwide. Its treatment remains a daunting
challenge, although significant progress has been made in existing treatments in recent …
challenge, although significant progress has been made in existing treatments in recent …
Exosomal circular RNAs: a chief culprit in cancer chemotherapy resistance
X Guo, C Gao, DH Yang, S Li - Drug Resistance Updates, 2023 - Elsevier
Chemotherapy is one of the primary treatments for malignant tumors. However, the acquired
drug resistance hinders clinical efficacy and leads to treatment failure in most patients …
drug resistance hinders clinical efficacy and leads to treatment failure in most patients …
Mechanistic pathogenesis of endothelial dysfunction in diabetic nephropathy and retinopathy
J Yang, Z Liu - Frontiers in endocrinology, 2022 - frontiersin.org
Diabetic nephropathy (DN) and diabetic retinopathy (DR) are microvascular complications of
diabetes. Microvascular endothelial cells are thought to be the major targets of …
diabetes. Microvascular endothelial cells are thought to be the major targets of …
The functional roles of the circRNA/Wnt axis in cancer
CircRNAs, covalently closed noncoding RNAs, are widely expressed in a wide range of
species ranging from viruses to plants to mammals. CircRNAs were enriched in the Wnt …
species ranging from viruses to plants to mammals. CircRNAs were enriched in the Wnt …
Going circular: history, present, and future of circRNAs in cancer
To date, thousands of highly abundant and conserved single-stranded RNA molecules
shaped into ring structures (circRNAs) have been identified. CircRNAs are multifunctional …
shaped into ring structures (circRNAs) have been identified. CircRNAs are multifunctional …
Circular RNA translation, a path to hidden proteome
Functional proteins in the cell are translated from the messenger RNA (mRNA) molecules,
constituting less than 5% of the cellular transcriptome. The majority of the RNA molecules in …
constituting less than 5% of the cellular transcriptome. The majority of the RNA molecules in …
CircRNAs in colorectal cancer: potential biomarkers and therapeutic targets
Y Zhang, J Luo, W Yang, WC Ye - Cell death & disease, 2023 - nature.com
Globally, colorectal cancer (CRC) is the third most prevalent cancer and the second leading
cause of cancer-related deaths. Circular RNAs (circRNAs) are single-stranded RNA with …
cause of cancer-related deaths. Circular RNAs (circRNAs) are single-stranded RNA with …
The role of noncoding RNAs in Parkinson's disease: biomarkers and associations with pathogenic pathways
MC Kuo, SCH Liu, YF Hsu, RM Wu - Journal of biomedical science, 2021 - Springer
The discovery of various noncoding RNAs (ncRNAs) and their biological implications is a
growing area in cell biology. Increasing evidence has revealed canonical and noncanonical …
growing area in cell biology. Increasing evidence has revealed canonical and noncanonical …
ADARs act as potent regulators of circular transcriptome in cancer
Circular RNAs (circRNAs) are produced by head-to-tail back-splicing which is mainly
facilitated by base-pairing of reverse complementary matches (RCMs) in circRNA flanking …
facilitated by base-pairing of reverse complementary matches (RCMs) in circRNA flanking …
Circular RNAs in immune response and viral infection
L Yan, YG Chen - Trends in Biochemical Sciences, 2020 - cell.com
Circular RNAs (circRNAs) are a diverse class of RNAs with varying sizes, cellular
abundance, and biological functions. Investigations from the past decade have revealed that …
abundance, and biological functions. Investigations from the past decade have revealed that …