[HTML][HTML] Anthocyanins: A comprehensive review of their chemical properties and health effects on cardiovascular and neurodegenerative diseases

R Mattioli, A Francioso, L Mosca, P Silva - Molecules, 2020 - mdpi.com
Anthocyanins are a class of water-soluble flavonoids widely present in fruits and vegetables.
Dietary sources of anthocyanins include red and purple berries, grapes, apples, plums …

[HTML][HTML] The Keap1-Nrf2 system: a mediator between oxidative stress and aging

C Yu, JH Xiao - Oxidative Medicine and Cellular Longevity, 2021 - hindawi.com
Oxidative stress, a term that describes the imbalance between oxidants and antioxidants,
leads to the disruption of redox signals and causes molecular damage. Increased oxidative …

Dietary polyphenols: Regulate the advanced glycation end products-RAGE axis and the microbiota-gut-brain axis to prevent neurodegenerative diseases

Y Li, Y Peng, Y Shen, Y Zhang, L Liu… - Critical Reviews in Food …, 2023 - Taylor & Francis
Advanced glycation end products (AGEs) are formed in non-enzymatic reaction, oxidation,
rearrangement and cross-linking between the active carbonyl groups of reducing sugars …

Anthocyanins and proanthocyanidins: chemical structures, food sources, bioactivities, and product development

Q Qi, M Chu, X Yu, Y Xie, Y Li, Y Du, X Liu… - Food Reviews …, 2023 - Taylor & Francis
Anthocyanins and proanthocyanidins are widespread in the plant kingdom and are involved
in important bioactivities, such as antioxidation. These flavonoids can reduce the risk of …

Targeting autophagy, oxidative stress, and ER stress for neurodegenerative disease treatment

Y Esmaeili, Z Yarjanli, F Pakniya, E Bidram… - Journal of Controlled …, 2022 - Elsevier
Protein homeostasis is a vital process for cell function and, therefore, disruption of the
molecular mechanisms involved in this process, such as autophagy, may contribute to …

[HTML][HTML] Anthocyanins: Promising natural products with diverse pharmacological activities

J Liu, H Zhou, L Song, Z Yang, M Qiu, J Wang, S Shi - Molecules, 2021 - mdpi.com
Anthocyanins are natural products that give color to plants. As natural plant pigments,
anthocyanins also have a series of health-promoting benefits. Many researchers have …

[HTML][HTML] The therapeutic potential of anthocyanins: current approaches based on their molecular mechanism of action

B Salehi, J Sharifi-Rad, F Cappellini, Ž Reiner… - Frontiers in …, 2020 - frontiersin.org
Anthocyanins are natural phenolic pigments with biological activity. They are well-known to
have potent antioxidant and antiinflammatory activity, which explains the various biological …

Implications of phosphoinositide 3-kinase-Akt (PI3K-Akt) pathway in the pathogenesis of Alzheimer's disease

M Kumar, N Bansal - Molecular neurobiology, 2022 - Springer
Alzheimer's disease (AD) is the foremost type of dementia that afflicts considerable morbidity
and mortality in aged population. Several transcription molecules, pathways, and molecular …

[HTML][HTML] The potential use of plant natural products and plant extracts with antioxidant properties for the prevention/treatment of neurodegenerative diseases: in vitro, in …

F Pohl, P Kong Thoo Lin - Molecules, 2018 - mdpi.com
Neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease and
Huntington's disease, present a major health issue and financial burden for health care …

[HTML][HTML] Anthocyanins and human health—a focus on oxidative stress, inflammation and disease

H Speer, NM D'Cunha, NI Alexopoulos, AJ McKune… - Antioxidants, 2020 - mdpi.com
Consumption of anthocyanins (ACNs), due to their antioxidant, anti-inflammatory and anti-
apoptotic effects, has been proposed for the prevention and treatment of several different …