Predictive power of cognitive biomarkers in neurodegenerative disease drug development: utility of the P300 event‐related potential

J Olichney, J Xia, KJ Church, HJ Moebius - Neural Plasticity, 2022 - Wiley Online Library
Neurodegenerative diseases, such as Alzheimer's disease (AD), and their associated
deterioration of cognitive function are common causes of disability. The slowly developing …

P300 parameters in major depressive disorder: A systematic review and meta-analysis

MK Arıkan, R İlhan, Ö Orhan, MT Esmeray… - The World Journal of …, 2024 - Taylor & Francis
Objectives Event-related potential measures have been extensively studied in mental
disorders. Among them, P300 amplitude and latency reflect impaired cognitive abilities in …

Prefrontal EEG slowing, synchronization, and ERP peak latency in association with predementia stages of Alzheimer's disease

J Choi, B Ku, DNT Doan, J Park, W Cha… - Frontiers in Aging …, 2023 - frontiersin.org
Background Early screening of elderly individuals who are at risk of dementia allows timely
medical interventions to prevent disease progression. The portable and low-cost …

Understanding the relationship between age-related hearing loss and Alzheimer's disease: A narrative review

HY Tarawneh, DMP Jayakody… - Journal of …, 2022 - content.iospress.com
Evidence suggests that hearing loss (HL), even at mild levels, increases the long-term risk of
cognitive decline and incident dementia. Hearing loss is one of the modifiable risk factors for …

Evaluation of event-related potentials in assessing cognitive functions of adult patients with epilepsy of unknown etiology

K Jeżowska-Jurczyk, P Jurczyk, S Budrewicz… - Journal of Clinical …, 2023 - mdpi.com
Background: Cognitive impairment (CI) is an important consequence of epilepsy. The aim of
the study was to assess cognitive performance in patients with epilepsy, using …

Pure tone audiometry and hearing loss in Alzheimer's disease: a meta-analysis

SS Kwok, XMT Nguyen, DD Wu, RA Mudar… - Frontiers in …, 2022 - frontiersin.org
An association between age-related hearing loss (ARHL) and Alzheimer's Disease (AD) has
been widely reported. However, the nature of this relationship remains poorly understood …

Comprehension of acoustically degraded speech in Alzheimer's disease and primary progressive aphasia

J Jiang, JCS Johnson, MC Requena-Komuro… - Brain, 2023 - academic.oup.com
Successful communication in daily life depends on accurate decoding of speech signals that
are acoustically degraded by challenging listening conditions. This process presents the …

Synapse-Related Serum and P300 Biomarkers Predict the Occurrence of Mild Cognitive Impairment in Depression

Z Xue, X Zhu, W Wu, Y Zhu, Y Xu… - … Disease and Treatment, 2024 - Taylor & Francis
Background Cognitive impairment is one of the common concomitant symptoms of
depression. The aims of the present study were to predict the occurrence of mild cognitive …

Clinical Assessment Tools for the Detection of Cognitive Impairment and Hearing Loss in the Ageing Population: A Scoping Review

MA Ferguson, K Nakano… - Clinical Interventions in …, 2023 - Taylor & Francis
Objective There is a strong association between cognitive impairment and hearing loss, both
highly prevalent in the ageing population. Early detection of both hearing loss and cognitive …

Adjunct Methods for Alzheimer's Disease Detection: A Review of Auditory Evoked Potentials

G Wei, X Tian, H Yang, Y Luo, G Liu… - Journal of …, 2024 - content.iospress.com
The auditory afferent pathway as a clinical marker of Alzheimer's disease (AD) has sparked
interest in investigating the relationship between age-related hearing loss (ARHL) and AD …