[HTML][HTML] Issues and updates: evaluating estrogen receptor-α, progesterone receptor, and HER2 in breast cancer
DC Allred - Modern Pathology, 2010 - Elsevier
There are currently three prognostic/predictive biomarkers used in routine clinical
management of patients with breast cancer, and their assessment is mandatory. They …
management of patients with breast cancer, and their assessment is mandatory. They …
The biology of progesterone receptor in the normal mammary gland and in breast cancer
AE Obr, DP Edwards - Molecular and cellular endocrinology, 2012 - Elsevier
This paper reviews work on progesterone and the progesterone receptor (PR) in the mouse
mammary gland that has been used extensively as an experimental model. Studies have led …
mammary gland that has been used extensively as an experimental model. Studies have led …
Complex actions of sex steroids in adipose tissue, the cardiovascular system, and brain: Insights from basic science and clinical studies
JL Turgeon, MC Carr, PM Maki… - Endocrine …, 2006 - academic.oup.com
Recent publications describing the results of the Women's Health Initiative (WHI) and other
studies reporting the impact of hormone therapy on aging women have spurred …
studies reporting the impact of hormone therapy on aging women have spurred …
Progesterone receptor action: defining a role in breast cancer
AR Daniel, CR Hagan, CA Lange - Expert review of endocrinology …, 2011 - Taylor & Francis
The ovarian steroid hormones, estradiol and progesterone, and their nuclear receptors
(estrogen receptor [ER] and progesterone receptor [PR]), are involved in breast cancer …
(estrogen receptor [ER] and progesterone receptor [PR]), are involved in breast cancer …
Progesterone and estrogen receptors: opposing prognostic indicators in meningiomas
S Pravdenkova, O Al-Mefty, J Sawyer… - Journal of neurosurgery, 2006 - thejns.org
Object The preponderance of progesterone receptors (PRs) and the scarcity of estrogen
receptors (ERs) in meningiomas are well known. The expression of PRs may relate to tumor …
receptors (ERs) in meningiomas are well known. The expression of PRs may relate to tumor …
Progesterone receptors upregulate Wnt-1 to induce epidermal growth factor receptor transactivation and c-Src-dependent sustained activation of Erk1/2 mitogen …
EJ Faivre, CA Lange - Molecular and cellular biology, 2007 - Taylor & Francis
Progesterone receptor (PR) ligand binding induces rapid and transient (5-to 10-min)
activation of cytosolic c-Src-Ras-Erk1/2 mitogen-activated protein kinase (MAPK) signaling …
activation of cytosolic c-Src-Ras-Erk1/2 mitogen-activated protein kinase (MAPK) signaling …
Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen-dependent gene signatures
P Kabos, J Finlay-Schultz, C Li, E Kline… - Breast cancer research …, 2012 - Springer
Bypassing estrogen receptor (ER) signaling during development of endocrine resistance
remains the most common cause of disease progression and mortality in breast cancer …
remains the most common cause of disease progression and mortality in breast cancer …
Progesterone receptor in non–small cell lung cancer—a potent prognostic factor and possible target for endocrine therapy
H Ishibashi, T Suzuki, S Suzuki, H Niikawa, L Lu, Y Miki… - Cancer research, 2005 - AACR
A possible involvement of gender-dependent factors has been postulated in development of
human non–small-cell lung cancers (NSCLC), but its details remain unclear. In this study …
human non–small-cell lung cancers (NSCLC), but its details remain unclear. In this study …
A Structural and in Vitro Characterization of Asoprisnil: A Selective Progesterone Receptor Modulator
KP Madauss, ET Grygielko, SJ Deng… - Molecular …, 2007 - academic.oup.com
Selective progesterone receptor modulators (SPRMs) have been suggested as therapeutic
agents for treatment of gynecological disorders. One such SPRM, asoprisnil, was recently in …
agents for treatment of gynecological disorders. One such SPRM, asoprisnil, was recently in …