[HTML][HTML] Spermatogonial stem cells and spermatogenesis in mice, monkeys and men
Continuous spermatogenesis in post-pubertal mammals is dependent on spermatogonial
stem cells (SSCs), which balance self-renewing divisions that maintain stem cell pool with …
stem cells (SSCs), which balance self-renewing divisions that maintain stem cell pool with …
Decoding the spermatogenesis program: new insights from transcriptomic analyses
Spermatogenesis is a complex differentiation process coordinated spatiotemporally across
and along seminiferous tubules. Cellular heterogeneity has made it challenging to obtain …
and along seminiferous tubules. Cellular heterogeneity has made it challenging to obtain …
[HTML][HTML] The mammalian spermatogenesis single-cell transcriptome, from spermatogonial stem cells to spermatids
Spermatogenesis is a complex and dynamic cellular differentiation process critical to male
reproduction and sustained by spermatogonial stem cells (SSCs). Although patterns of gene …
reproduction and sustained by spermatogonial stem cells (SSCs). Although patterns of gene …
A comprehensive roadmap of murine spermatogenesis defined by single-cell RNA-seq
Spermatogenesis requires intricate interactions between the germline and somatic cells.
Within a given cross section of a seminiferous tubule, multiple germ and somatic cell types …
Within a given cross section of a seminiferous tubule, multiple germ and somatic cell types …
Chromatin and single-cell RNA-seq profiling reveal dynamic signaling and metabolic transitions during human spermatogonial stem cell development
Human adult spermatogonial stem cells (hSSCs) must balance self-renewal and
differentiation. To understand how this is achieved, we profiled DNA methylation and open …
differentiation. To understand how this is achieved, we profiled DNA methylation and open …
Unraveling transcriptome dynamics in human spermatogenesis
SZ Jan, TL Vormer, A Jongejan, MD Röling… - …, 2017 - journals.biologists.com
Spermatogenesis is a dynamic developmental process that includes stem cell proliferation
and differentiation, meiotic cell divisions and extreme chromatin condensation. Although …
and differentiation, meiotic cell divisions and extreme chromatin condensation. Although …
A human neurodevelopmental model for Williams syndrome
Williams syndrome is a genetic neurodevelopmental disorder characterized by an
uncommon hypersociability and a mosaic of retained and compromised linguistic and …
uncommon hypersociability and a mosaic of retained and compromised linguistic and …
ID4 levels dictate the stem cell state in mouse spermatogonia
Spermatogenesis is a classic model of cycling cell lineages that depend on a balance
between stem cell self-renewal for continuity and the formation of progenitors as the initial …
between stem cell self-renewal for continuity and the formation of progenitors as the initial …
Spermatogonial stem cells: updates from specification to clinical relevance
Human spermatogonia are target for exploration of adult stem cell characteristics and
potential source for the development of therapeutic applications. Almost 50 years ago, Yves …
potential source for the development of therapeutic applications. Almost 50 years ago, Yves …
Developmental kinetics and transcriptome dynamics of stem cell specification in the spermatogenic lineage
Continuity, robustness, and regeneration of cell lineages relies on stem cell pools that are
established during development. For the mammalian spermatogenic lineage, a foundational …
established during development. For the mammalian spermatogenic lineage, a foundational …