PURPOSE: Colorectal cancer is the fourth most common cancer and the second leading
cause of cancer death in the United States. Accumulating evidence indicates that …

We report that CpG island methylation, an epigenetic modification of DNA known to correlate
closely with silencing of gene transcription, appears in the oestrogen receptor (ER) gene in …

The aim of this study was to identify the mode of presentation and incidence of colorectal
cancer in pregnancy (CRC-p), assess the outcomes of the mother and foetus according to …

Colorectal carcinoma presenting in pregnancy is an uncommon disease that is reported to
be associated with an extremely poor prognosis. To better characterize this disease, we …

Since flaxseed ingestion produces potentially anticarcinogenic lignans in the colon, this
study determined whether flaxseed decreases the risk for colon carcinogenesis. Following a …

Evidence of a role for steroid hormones and reproduction in colon neoplasia remains
tantalizing but unclear. Hormone replacement therapy (HRT) has been reported in a number …

Background. The immunoreactivity for progesterone receptors (PR) of the majority of
endocrine cells of the human pancreas has prompted the authors to investigate if PR …

Colorectal carcinoma shows several sex‐related differences with regard to incidence,
response to chemotherapy and microsatellite instability. These differences may relate to …

Existing data suggest that there is a hormonal basis to the cause of colon cancer. In the
present study, we evaluated the presence of estrogen receptors (ERs) and progesterone …

The incidence of colorectal cancer (CRC) is lower in women than in men, and sex steroids
can be considered contributing factors because oral contraception usage and estrogen …