Since its introduction in the 1950s, the forced oscillation technique (FOT) and the
measurement of respiratory impedance have evolved into powerful tools for the assessment …

Segmentation of lungs with acute respiratory distress syndrome (ARDS) is a challenging
task due to diffuse opacification in dependent regions which results in little to no contrast at …

The ability to maintain adequate gas exchange depends on the relatively homogeneous
distribution of inhaled gas throughout the lung. Structural alterations associated with many …

Acute lung injury is characterized by heterogeneity of regional mechanical properties, which
is thought to be correlated with disease severity. The feasibility of using respiratory input …

Regional specific lung volume change (sVol), defined as the regional tidal volume divided
by the regional end-expiratory gas volume, is a key variable in lung mechanics and in the …

To determine the impact of ventilation frequency, lung volume, and parenchymal stiffness on
ventilation distribution, we developed an anatomically-based computational model of the …

Introduction It is well established that during mechanical ventilation of patients with acute
respiratory distress syndrome cyclic recruitment/derecruitment and overdistension are …

Computed tomography (CT) is routinely used for diagnosing lung disease and developing
treatment plans using images of intricate lung structure with submillimeter resolution …

Over the last century, the diagnosis and monitoring of respiratory diseases has been an
ongoing challenge and requires constant improvement. The assessment of patients with …

The forced oscillation technique (FOT) is a non-invasive technique for the assessment of
respiratory mechanics. Since it does not require patient's collaboration and it is not affected …