Alzheimer's disease (AD) is a chronic neurodegenerative disease and the most frequent
cause of progressive dementia in senior adults. It is characterized by memory loss and …

Essential oils have been used in multiple ways, ie, inhaling, topically applying on the skin,
and drinking. Thus, there are three major routes of intake or application involved: the …

Brown adipose tissue (BAT) and beige fat function in energy expenditure in part due to their
role in thermoregulation, making these tissues attractive targets for treating obesity and …

Activation of nociceptor sensory neurons by noxious stimuli both triggers pain and increases
capillary permeability and blood flow to produce neurogenic inflammation,, but whether …

The capsaicin (vanilloid) receptor, TRPV1, is a heat-activated cation channel modulated by
inflammatory mediators and contributes to acute and chronic pain. TRPV1 channel is one of …

Chronic pain and pruritus are highly disabling pathologies that still lack appropriate
therapeutic intervention. At cellular level the transduction and transmission of pain and …

Niacin (vitamin B3) is an essential nutrient that treats pellagra, and prior to the advent of
statins, niacin was commonly used to counter dyslipidemia. Recent evidence has posited …

The heterocyclic vanilloid compound capsaicin is responsible for the spicy and pungent
flavor of chili peppers. Several convergent studies have shown that capsaicin suppresses …

Capsaicin (CAP) rich diets may help with a variety of human pathophysiological conditions;
however, CAP administration is difficult due to its high pungency and limited water solubility …

Although TRPV1 ion channel has been attracting researchers' attention for many years, its
functions in animal organisms, the principles of regulation, and the involvement in …