Interleukin 23 receptor: Expression and regulation in immune cells
I Mezghiche, H Yahia‐Cherbal… - European Journal of …, 2024 - Wiley Online Library
The importance of IL‐23 and its specific receptor, IL‐23R, in the pathogenesis of several
chronic inflammatory diseases has been established, but the underlying pathological …
chronic inflammatory diseases has been established, but the underlying pathological …
Deciphering the developmental trajectory of tissue-resident Foxp3+ regulatory T cells
F Alvarez, Z Liu, A Bay, CA Piccirillo - Frontiers in Immunology, 2024 - frontiersin.org
Foxp3+ TREG cells have been at the focus of intense investigation for their recognized roles
in preventing autoimmunity, facilitating tissue recuperation following injury, and …
in preventing autoimmunity, facilitating tissue recuperation following injury, and …
B cell immune profiles in dysbiotic vermiform appendixes of pancreatic cancer patients
EE Vietsch, D Latifi, M Verheij… - Frontiers in …, 2023 - frontiersin.org
Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest solid tumors and is
resistant to immunotherapy. B cells play an essential role in PDAC progression and immune …
resistant to immunotherapy. B cells play an essential role in PDAC progression and immune …
CTLA-4-expressing ILC3s restrain interleukin-23-mediated inflammation
Abstract Interleukin (IL-) 23 is a major mediator and therapeutic target in chronic
inflammatory diseases that also elicits tissue protection in the intestine at homeostasis or …
inflammatory diseases that also elicits tissue protection in the intestine at homeostasis or …
IL-23 receptor signaling licenses group 3-like innate lymphoid cells to restrict a live-attenuated oral Chlamydia vaccine in the gut
Y He, Y Wang, R He, AM Abdelsalam… - Infection and …, 2023 - Am Soc Microbiol
An IFNγ-susceptible mutant of Chlamydia muridarum is attenuated in pathogenicity in the
genital tract and was recently licensed as an intr acellular O ral vaccine v ector or intrOv …
genital tract and was recently licensed as an intr acellular O ral vaccine v ector or intrOv …
Identification of the grass carp interleukin-23 receptor and its proinflammatory role in intestinal inflammation
P Han, J Tang, X Xu, P Meng, K Wu, B Sun… - International Journal of …, 2024 - Elsevier
Abstract The interleukin 23 receptor (IL-23R) is associated with a variety of inflammatory
diseases in humans and other mammals. However, whether IL-23R is involved in …
diseases in humans and other mammals. However, whether IL-23R is involved in …
[HTML][HTML] Tolerogenic dendritic cell-mediated regulatory T cell differentiation by Chinese herbal formulation attenuates colitis progression
C Huang, C Lyu, HL Mok, Y Xu, KW Cheng… - Journal of Advanced …, 2024 - Elsevier
Introduction Ulcerative colitis (UC) is a chronic inflammatory disease characterized by loss of
immune tolerance to luminal antigens and progressive intestinal tissue injury. Thus, the re …
immune tolerance to luminal antigens and progressive intestinal tissue injury. Thus, the re …
The upregulation of VGF enhances the progression of oral squamous carcinoma
Background Oral squamous cell carcinoma (OSCC) is a prevalent neoplasm worldwide,
necessitating a deeper understanding of its pathogenesis. VGF nerve growth factor …
necessitating a deeper understanding of its pathogenesis. VGF nerve growth factor …
[HTML][HTML] Eosinophils exert antitumorigenic effects in the development of esophageal squamous cell carcinoma
J Jacobse, Z Aziz, L Sun, J Chaparro, JM Pilat… - Cellular and molecular …, 2023 - Elsevier
Background and Aims Eosinophils are present in several solid tumors and have context-
dependent function. Our aim is to define the contribution of eosinophils in esophageal …
dependent function. Our aim is to define the contribution of eosinophils in esophageal …
[HTML][HTML] IL-23 Exerts Dominant Pathogenic Functions in Crohn's Disease-Ileitis
L Iliopoulou, E Lianopoulou, G Kollias - Mucosal Immunology, 2024 - Elsevier
Abstract Crohn's disease (CD), a main form of Inflammatory Bowel Diseases (IBD) is a
chronic inflammatory disorder, mainly affecting the ileum. IL-12 and IL-23 are both targeted …
chronic inflammatory disorder, mainly affecting the ileum. IL-12 and IL-23 are both targeted …