Neurodegeneration, the slow and progressive dysfunction and loss of neurons and axons in
the central nervous system, is the primary pathological feature of acute and chronic …

A growing body of epidemiologic and experimental data point to chronic bacterial and viral
infections as possible risk factors for neurodegenerative diseases, including Alzheimer's …

Background Multiple sclerosis (MS) appears to develop in genetically susceptible
individuals as a result of environmental exposures. Epstein-Barr virus (EBV) infection is an …

The cause and the pathogenic mechanisms leading to multiple sclerosis (MS), a chronic
inflammatory disease of the central nervous system (CNS), are still under scrutiny. During …

The cause of multiple sclerosis (MS) is elusive. However, clues to the pathogenesis of this
condition have traditionally been derived from the basic pathologic characterization of the …

Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system
(CNS) that is thought to be caused by a combination of genetic and environmental factors …

Multiple sclerosis (MS) is considered a prototypic autoimmune disease of the central
nervous system (CNS). A complex genetic background with the HLA-DR15 haplotype as the …

During the past 10 years, much attention has been focused towards elucidating the impact of
Toll-like receptors (TLRs) in central nervous system (CNS) innate immunity. TLR signaling …

Recent epidemiological and immunological studies provide evidence for an association
between Epstein–Barr virus infection and multiple sclerosis, suggesting a role of Epstein …

Multiple sclerosis is an inflammatory, demyelinating, central nervous system disease
mediated by myelin-specific T cells. Environmental triggers that cause the breakdown of …