Nowadays, nitrogenous heterocyclic molecules have attracted a great deal of interest
among medicinal chemists. Among these potential heterocyclic drugs, benzimidazole …

The data on the chemical structures, biological effects, and use of cannabinoids on the
illegal market of new psychoactive substances were generalized. An extended classification …

Two 3D quantitative structure–activity relationships (3D-QSAR) models for predicting
Cannabinoid receptor 1 and 2 (CB1 and CB2) ligands have been produced by way of …

Herein we report the design, synthesis, bioinformatic and biological studies of
benzimidazole and benzothiophene derivatives as new cannabinoid receptor ligands. To …

Quantitative structure− activity relationship (QSAR) modeled the biological activities of 30
cannabinoids with quantum similarity descriptors (QSD) and Comparative Molecular Field …

The preceding years have brought an exponential increase in our understanding of the
endocannabinoid system (ECS), including the knowledge of CB1 and CB2 cannabinoid …

The therapeutic use of Cannabis dates back to ancient times and this plant has been used
for centuries as remedy for a large number of diseases. Today it is well known that biological …

A new and efficient method for preparation of benzimidazoles, benzoxazoles, and
benzothiazoles from reactions of different carboxylic acids with o-phenylenediamine, o …

Fatty Acid Amide Hydrolase (FAAH) is one of the main enzymes responsible for
endocannabinoid metabolism. Inhibition of FAAH increases endogenous levels of fatty acid …

Obesity is the fifth primary hazard for mortality in the world; hence different therapeutic
targets are explored to overcome this problem. Endocannabinoid is identified as the …