Clinical practice guidelines for therapeutic drug monitoring of vancomycin in the framework of model-informed precision dosing: a consensus review by the Japanese …

K Matsumoto, K Oda, K Shoji, Y Hanai, Y Takahashi… - Pharmaceutics, 2022 - mdpi.com
Background: To promote model-informed precision dosing (MIPD) for vancomycin (VCM),
we developed statements for therapeutic drug monitoring (TDM). Methods: Ten clinical …

Can population pharmacokinetics of antibiotics be extrapolated? Implications of external evaluations

Y Cheng, C Wang, Z Li, Y Pan, M Liu, Z Jiao - Clinical pharmacokinetics, 2021 - Springer
Background and objective External evaluation is an important issue in the population
pharmacokinetic analysis of antibiotics. The purpose of this review was to summarize the …

Pharmacokinetics and pharmacodynamics of peptide antibiotics

X Bian, X Qu, J Zhang, SC Nang, PJ Bergen… - Advanced drug delivery …, 2022 - Elsevier
Antimicrobial resistance is a major global health challenge. As few new efficacious
antibiotics will become available in the near future, peptide antibiotics continue to be major …

External evaluation of population pharmacokinetic models for precision dosing: current state and knowledge gaps

M El Hassani, A Marsot - Clinical Pharmacokinetics, 2023 - Springer
Predicting drug exposures using population pharmacokinetic models through Bayesian
forecasting software can improve individual pharmacokinetic/pharmacodynamic target …

An update on population pharmacokinetic analyses of vancomycin, part II: in pediatric patients

A Aljutayli, I El-Haffaf, A Marsot, F Nekka - Clinical pharmacokinetics, 2022 - Springer
Vancomycin is widely used in pediatric patients, however, large inter-and intraindividual
variability are observed in vancomycin pharmacokinetics, affecting proper therapeutic …

Population pharmacokinetics of tigecycline: a systematic review

CC Zhou, F Huang, JM Zhang… - Drug Design …, 2023 - Taylor & Francis
Although tigecycline is widely used in clinical practice, its efficiency and optimal dosage
regimens remain controversial. The purpose of this article was to help guide tigecycline …

Application of machine learning classification to improve the performance of vancomycin therapeutic drug monitoring

S Lee, M Song, J Han, D Lee, BH Kim - Pharmaceutics, 2022 - mdpi.com
Bayesian therapeutic drug monitoring (TDM) software uses a reported pharmacokinetic (PK)
model as prior information. Since its estimation is based on the Bayesian method, the …

Should the trough concentration of vancomycin be abandoned in therapeutic drug monitoring? A multicentre, retrospective study of critically ill patients without any …

Z Yu, J Liu, H Yu, L Zhou, Y Zhao, L Zhong… - International Journal of …, 2023 - Elsevier
Background There are conflicts in guideline recommendations about the value and range of
vancomycin trough concentration during therapeutic drug monitoring (TDM). This …

Bayesian prediction-based individualized dosing of anti-methicillin-resistant Staphylococcus aureus treatment: recent advancements and prospects in therapeutic …

K Oda, H Saito, H Jono - Pharmacology & Therapeutics, 2023 - Elsevier
As one of the efficient techniques for TDM, the population pharmacokinetic (popPK) model
approach for dose individualization has been developed due to the rapidly growing …

Pharmacokinetic equations versus Bayesian guided vancomycin monitoring: pharmacokinetic model and model‐informed precision dosing trial simulations

A Aljutayli, DJG Thirion, G Bonnefois… - Clinical and …, 2022 - Wiley Online Library
The recently released revised vancomycin consensus guideline endorsed area under the
concentration‐time curve (AUC) guided monitoring. Means to AUC‐guided monitoring …